177971-33-4

Upstream product

• 7051-16-3 1-chloro-3,5-dimethoxybenzene 
• 177971-32-3 (2R)-2-methyl-1-(p-tolylsulfonyl)aziridine 

Downstream Products

• 177971-34-5 (1R)-2-(3,5-dimethoxyphenyl)-1-methylethylamine 
• 153379-47-6 (R)-N-<1-(3,5-dimethoxyphenyl)-2-propyl>acetamide 
• 177971-38-9 (1S-cis)-1,2,3,4-tetrahydro-1,2,3-trimethyl-6,8-bis(phenylmethoxy)isoquinoline 
• 177971-39-0 (1S-cis)-1,2,3,4-tetrahydro-5-iodo-1,2,3-trimethyl-6,8-bis(phenylmethoxy)isoquinoline 
• 177971-37-8 (1S-cis)-N-carbethoxy-1,2,3,4-tetrahydro-1,3-dimethyl-6,8-bis(phenylmethoy)isoquinoline 

Relevant academic research and scientific papers

Total synthesis of michellamines A-C, korupensamines A-D, and ancistrobrevine B

Efficient syntheses of the title compounds have been developed. Several strategies for preparation of each of the naphthalene and tetrahydroisoquinoline (THIQ) portions were developed. Initial attempts to use benzyne plus furan cycloaddition reactions wer

Total synthesis of (ent)-korupensamine D

The first total synthesis of the enantiomer of the natural product, korupensamine D (16R), is described. The key steps include a highly efficient preparation of the enantiomerically pure primary amine 4 via the ring opening of aziridine 2 with an arylcupr