17811-64-2Relevant academic research and scientific papers
N-(Arylsulfonyl)trihaloacetimidoyl Chlorides and Their Reactions with Phosphites
Rassukana, Yuliya V.,Onys'Ko, Petro P.,Grechukha, Anatolii G.,Sinitsa, Anatolii D.
, p. 4181 - 4186 (2003)
We have developed a convenient synthetic approach to highly reactive N-(arylsulfonyl)trichloro- and -trifluoroacetimidoyl chlorides 2 by reacting the corresponding N-acylsulfonamides with PCl5. The interaction of the imidoyl chlorides with phos
Development of an acyl sulfonamide anti-proliferative agent, ly573636 ? na
Yates, Matthew H.,Kallman, Neil J.,Ley, Christopher P.,Wei, Jeffrey N.
experimental part, p. 255 - 262 (2010/04/22)
The synthesis of 5-bromo-thiophene-2-sulfonic acid 2,4-dichlo- robenzoylamide sodium salt on multikilogram scale is described. The initial clinical supplies were made using carbonyl diimidazole to converge the two fragments. A more efficient acid chloride process has been developed, which also provides better control of impurities and color throughout the synthesis.
Oxidation of N(1-hydroxypolychloroethyl)sulfonamides
Rozentsveig,Rozentsveig,Levkovskaya,Mirskova
, p. 1284 - 1286 (2007/10/03)
N-(2,2,2-Trichloro-1-hydroxyethyl)- and N-(2,2-dichloro-1-hydroxy-2-phenylethyl)arenesulfonamides are oxidized with chromium(VI) oxide to give, respectively, N-(arylsulfonyl)trichloroacetamides and N-(arylsulfbnyl)dichloro(phenyl)acetamidcs. Under analogo
