6536-23-8Relevant articles and documents
The synthesis of bicyclic 1,2,3,4-tetrahydro-1,4-benzodiazepin-5-ones from 2-(o-nitrobenzoyl)-1,2-thiazine-1-oxide precursors
Hemming, Karl,Loukou, Christina
, p. 3349 - 3357 (2007/10/03)
Sulfinylation of o-nitrobenzamide and subsequent hetero Diels-Alder reaction gave a series of 2-(o-nitrobenzoyl)-1,2-thiazine-1-oxides. The 2-(o-nitrobenzoyl)-1,2-thiazine-1-oxides undergo a ring opening reaction with phenyl magnesium bromide to give allylic sulfoxides, which, after [2,3]-sigmatropic rearrangement and desulfurisation, furnish unsaturated vicinal N-(o-nitrobenzoyl)-1,2-amino alcohols. Oxidation of the alcohol and reductive ring closure gave a series of bicyclic 1,2,3,4-tetrahydro-1,4- benzodiazepin-5-ones, a subset of the 'privileged' 1,4-benzodiazepine structure. A 4-hydroxy-1,2,5-benzothiadiazepin-1,1-dioxide was synthesised by the same route starting from o-nitrobenzenesulfonamide.
REACTIONS OF α,α,ω-TRIHYDROPOLYFLUOROALKOXYTRIFLUOROSULFURANES WITH PRIMARY AMINES AND AMIDES
Markovskii, L.N.,Tovstenko, V.I.,Pashinnik, V.E.,Mel'nichuk, E.A.,Makarenko, A.G.,Shermolovich, Yu.G.
, p. 660 - 663 (2007/10/02)
α,α,ω-Trihydropolyfluoroalkoxytrifluorosulfuranes react with primary amides or their N,N'-di(trimethylsilyl) derivatives to form acid fluoride derivatives of N-substituted polyfluoroalkyliminosulfurous acids.The thermal stability of these products depends
NEW FACILE SYNTHESIS OF N-SULFINYLAMINE DERIVATIVES USING N,N'-SULFINYLBISIMIDAZOLE AND N-(CHLOROSULFINYL)IMIDAZOLE
Kim, Yong Hae,Shin, Jai Moo
, p. 3821 - 3824 (2007/10/02)
Treatment of amine derivatives such as amines, sulfonamides, and amides with N,N'-sulfinylbisimidazole (1) and N-(chlorosulfinyl)imidazole (2) in situ respectively gives the corresponding N-sulfinylamine derivatives (3): the latter reaction using N-(chlor
