178151-42-3

Basic information

• Product Name: (1S,2R)-1,2-diphenyl-2-<(1,1-dimethylethyl)dimethylsiloxy>ethylamine
• Synonyms: (1S,2R)-1,2-diphenyl-2-<(1,1-dimethylethyl)dimethylsiloxy>ethylamine
• CAS NO: 178151-42-3
• Molecular Weight: 327.542
• Mol File: 178151-42-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (1S,2R)-1,2-diphenyl-2-<(1,1-dimethylethyl)dimethylsiloxy>ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,2R)-1,2-diphenyl-2-<(1,1-dimethylethyl)dimethylsiloxy>ethylamine(178151-42-3)
• EPA Substance Registry System: (1S,2R)-1,2-diphenyl-2-<(1,1-dimethylethyl)dimethylsiloxy>ethylamine(178151-42-3)

Safety Data

• Hazardous Substances Data: 178151-42-3(Hazardous Substances Data)

Upstream product

• 1439-07-2 (R,R)-trans-stilbene epoxide 
• 133522-22-2 (1R,2S)-2-azido-1,2-diphenylethan-1-ol 
• 23190-16-1 (1R,2S)-2-Amino-1,2-diphenylethanol 
• 18162-48-6 tert-butyldimethylsilyl chloride 
• 177977-65-0 ((1R,2S)-2-Azido-1,2-diphenyl-ethoxy)-tert-butyl-dimethyl-silane 

Downstream Products

• 467214-85-3 1-[2-(tert-butyl-dimethyl-silanyloxy)-1,2-diphenyl-ethyl]-2-propyl-2,3,4,6,7,8-hexahydro-1H-quinolin-5-one 
• 467214-86-4 (S)-1-((1S,2R)-2-Hydroxy-1,2-diphenyl-ethyl)-2-propyl-2,3,4,6,7,8-hexahydro-1H-quinolin-5-one 
• 264903-43-7 1-[2-(tert-butyl-dimethyl-silanyloxy)-1,2-diphenyl-ethyl]-2-propyl-2,6,7,8-tetrahydro-1H-quinolin-5-one 
• 894809-31-5 1-[(1R,2S)-(2-t-butyldimethylsilyloxy-1,2-diphenylethyl)]-2-[(1S,2S)-(1,2-diphenylethyl-2-ethoxycarbonylamino)]thioamide 
• 894809-32-6 (4S,5S)-2-[(E)-(1S,2R)-(2-t-butyldimethylsilyloxy-1,2-diphenylethyl)]imino-4,5-diphenyl-1-ethoxycarbonylimidazolidine 
• 894809-33-7 (4S,5S)-4,5-diphenyl-2-[(E)-(1S,2R)-(1,2-diphenyl-2-hydroxyethyl)]imino-1-ethoxycarbonylimidazolidine 
• 894809-34-8 (2S,3S,7S,8S)-6-ethoxycarbonyl-2,3,7,8-tetraphenyl-1,4,6-triazabicyclo[3.3.0]oct-4-ene 
• 264903-42-6 3-[(1S,2R)-2-(tert-Butyl-dimethyl-silanyloxy)-1,2-diphenyl-ethylamino]-cyclohex-2-enone 

Relevant articles and documents

Stereodivergent approach to both c2,8a-syn and c2,8a-anti relative stereochemical manifolds in the lepadin family via a ticl4-promoted aza-[3+3] annulation

Details in developing a stereodivergent approach to the lepadin family and establishing an entry to both C2,8a-syn and C2,8a-anti relative stereochemical manifolds through a common intermediate are described here. This works paves the foundation for const

Asymmetric catalysis via chiral aziridines

The chiral bis(aziridines) 4, 6 and 7 have been synthesized and evaluated as chelating ligands for a variety of asymmetric transformations mediated by metals. The processes studied were the asymmetric addition of osmium tetroxide to olefins, copper-catalyzed asymmetric cyclopropanation and aziridination, palladium-catalyzed asymmetric allylic alkylation and asymmetric 1,2-addition of organolithium reagents to imines. In the best cases an enantiomeric excess >95% was obtained. Acta Chemica Scandinavica 1996.