178160-25-3

Upstream product

• 61346-19-8 5-nitroindazolin-3-one 
• 100-39-0 benzyl bromide 
• 178160-22-0 ethyl 3-hydroxy-5-nitro-1H-indazole-1-carboxylate 
• 178160-23-1 1-(4-Methoxybenzyl)-5-nitro-1H-indazol-3-ol 
• 178160-32-2 2-Benzyl-1-(4-methoxybenzyl)-5-nitro-1,2-dihydro-3H-indazol-3-one 

Downstream Products

• 1210312-45-0 C₂₁H₁₇N₃O₃ 
• 1210312-50-7 C₁₇H₁₇N₃O₃ 
• 1210312-32-5 VATR-1 
• 1210312-43-8 C₁₇H₁₇N₃O₃ 
• 1416330-19-2 C₁₇H₁₇N₃O₃ 
• 1391707-83-7 2-benzyl-1-butyl-5-nitroindazolin-3-one 
• 1416330-25-0 C₁₈H₁₉N₃O₃ 
• 1210312-48-3 C₁₉H₂₁N₃O₃ 
• 1352138-00-1 VATR-4 

Relevant academic research and scientific papers

Selective synthesis of 2-substituted indazolin-3-ones without N-1 protection

N-2-Alkylation of indazolin-3-ones was performed in neutral conditions. This method represents a direct and efficient entry to a class of compounds having interesting biological activities, avoiding the generally required N-1 protection.

Synthesis, biological evaluation and chemometric analysis of indazole derivatives. 1,2-Disubstituted 5-nitroindazolinones, new prototypes of antichagasic drug

Chagas disease chemotherapy, currently based on only two drugs, nifurtimox and benznidazole, is far from satisfactory and therefore the development of new antichagasic compounds remains an important goal. On the basis of antichagasic properties previously

Analogues of cytostatic, fused indazolinones: Synthesis, conformational analysis and cytostatic activity against HeLa cells of some 1-substituted indazolols, 2-substituted indazolinones, and related compounds

A number of indazol-3-ol and indazolin-3-one derivatives were designed as open-chain analogues of some previously studied cytostatic tetranuclear indazolinones. The former were prepared by starting with alkylation of the parent indazolinones (11 or its 5-