178160-25-3Relevant articles and documents
Selective synthesis of 2-substituted indazolin-3-ones without N-1 protection
Arán, Vicente J.,Díez-Barra, Enrique,De La Hoz, Antonio,Sánchez-Verdú, Prado
, p. 129 - 136 (1997)
N-2-Alkylation of indazolin-3-ones was performed in neutral conditions. This method represents a direct and efficient entry to a class of compounds having interesting biological activities, avoiding the generally required N-1 protection.
Analogues of cytostatic, fused indazolinones: Synthesis, conformational analysis and cytostatic activity against HeLa cells of some 1-substituted indazolols, 2-substituted indazolinones, and related compounds
Aran, Vicente J.,Flores, Maria,Munoz, Pilar,Paez, Juan A.,Sanchez-Verdu, Prado,Stud, Manfred
, p. 683 - 691 (2007/10/03)
A number of indazol-3-ol and indazolin-3-one derivatives were designed as open-chain analogues of some previously studied cytostatic tetranuclear indazolinones. The former were prepared by starting with alkylation of the parent indazolinones (11 or its 5-