178181-89-0Relevant academic research and scientific papers
Stereoselective conjugate addition of carbon nucleophiles to chiral (E)-nitroalkenes bearing a γ-stereocenter. Origins of the observed anti selectivity
Ayerbe, Mirari,Morao, Inaki,Arrieta, Ana,Linden, Anthony,Cossio, Fernando P.
, p. 3055 - 3058 (1996)
The reaction between different organometallic carbon nucleophiles and chiral (E)-nitroalkenes has been studied. Anti selectivities have been observed in all cases. SCF-MO calculations suggest that the observed stereocontrol relies on the anti disposition of a donor group (methyl or hydrogen) with respect to the C-C bond in formation.
