178207-64-2Relevant academic research and scientific papers
Synthesis and biological evaluation of N(α)-(4-amino-4-deoxy-10- methylpteroyl)-DL-4,4-difluoroornithine
Tsukamoto,Haile,McGuire,Coward
, p. 2536 - 2540 (1996)
N(α)-(4-Amino-4-deoxy-10-methylpteroyl)-DL-4,4-difluoroornithine (AMPte- DL-4,4-F2Orn, 4) was synthesized and evaluated as an inhibitor of human folylpoly-γ-glutamate synthetase (FPGS), dihydrofolate reductase (DHFR), and cell growth. Synthesis
