17823-64-2Relevant academic research and scientific papers
One-Pot Synthesis and Antiproliferative Activity of Highly Functionalized Pyrazole Derivatives
Lusardi, Matteo,Rotolo, Chiara,Ponassi, Marco,Iervasi, Erika,Rosano, Camillo,Spallarossa, Andrea
, (2022/02/05)
A series of highly functionalized pyrazole derivatives has been prepared by a one-pot, versatile and regioselective procedure. Pyrazoles 1–29 were tested in cell-based assay to assess their antiproliferative activity against a panel of tumour cells. Addit
Design and synthesis of potent N-phenylpyrimidine derivatives for the treatment of skin cancer
Chaube, Udit J.,Vyas, Vivek K.,Bhatt, Hardik G.
, p. 10285 - 10297 (2016/02/09)
The development of novel synthetic compounds for the treatment of skin cancer is much needed, as there is a sudden rise in the incidence of skin cancer throughout the world and the available chemotherapy is facing problems of resistance. Hence, present re
Regiospecific Syntheses of Glycocitrine-II and Acronycine
Anand, Ramesh C.,Sinha, Arun K.
, p. 2339 - 2342 (2007/10/02)
Regiospecific syntheses of glcyocitrine-II and acronycine have been achieved from 3-acetyl-4-chloro-2-cyanomethylquinoline which, in turn, has been prepared by two different routes, from the aniline and anthranilic acid derivatives methyl 3-anilino-2-cyano-3-(methylthio)prop-2-enoate and methyl N-(1-methyl-3-oxobut-1-enyl)anthranilate.
Synthesis of Quinoline Derivatives Using Ketene Dithioacetals
Tominaga, Yoshinori,Michioka, Takeharu,Moriyama, Kohu,Hosomi, Akira
, p. 1217 - 1225 (2007/10/02)
Methyl 3-(N-arylamino)-2-cyano-3-methylthioacrylates 3a-h, which are readily prepared by the reaction of the ketene dithioacetal, methyl 2-cyano-3,3-bis(methylthio)acrylate (1) with arylamines, was heated at reflux in diphenyl ether to give the correspond
