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METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE, with the molecular formula C8H11NO2S2, is a clear, colorless liquid characterized by a pungent odor. This chemical compound is primarily utilized in the synthesis of a variety of organic compounds and polymers, and it plays a significant role in the production of adhesives, coatings, and other industrial products. Due to its irritant properties to the skin and eyes, and potential to cause respiratory irritation upon inhalation, it requires careful handling and storage to mitigate exposure and associated risks.

3490-92-4

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3490-92-4 Usage

Uses

Used in Chemical Synthesis:
METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE is used as a key intermediate in the synthesis of various organic compounds and polymers, contributing to the development of a wide range of chemical products.
Used in Adhesives Production:
In the Adhesives Industry, METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE is used as a component in the formulation of adhesives, enhancing their bonding properties and performance characteristics.
Used in Coatings Production:
Within the Coatings Industry, METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE is employed as a constituent in the production of coatings, improving their durability, adhesion, and resistance to environmental factors.
Used in Other Industrial Products:
METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE is also utilized in the manufacturing of various other industrial products, where its chemical properties contribute to the performance and quality of the final goods.

Check Digit Verification of cas no

The CAS Registry Mumber 3490-92-4 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,4,9 and 0 respectively; the second part has 2 digits, 9 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 3490-92:
(6*3)+(5*4)+(4*9)+(3*0)+(2*9)+(1*2)=94
94 % 10 = 4
So 3490-92-4 is a valid CAS Registry Number.
InChI:InChI=1/C7H9NO2S2/c1-10-6(9)5(4-8)7(11-2)12-3/h1-3H3

3490-92-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-Cyano-3,3-bis-methylsulfanyl-acrylic acid methyl ester

1.2 Other means of identification

Product number -
Other names methyl 2-cyano-3,3-bis(methylsulfanyl)prop-2-enoate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3490-92-4 SDS

3490-92-4Relevant academic research and scientific papers

HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS

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Paragraph 00411, (2021/04/01)

The application relates to lipids of Formula (A-1) and compositions involving the same. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) include such a lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) further including therapeutic and/ or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

MODULATORS OF METHYL MODIFYING ENZYMES, COMPOSITIONS AND USES THEREOF

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Paragraph 0090; 0091, (2019/11/05)

Provided are novel compounds of Formula (I): and pharmaceutically acceptable salts thereof, which are useful for treating a variety of diseases, disorders or conditions, associated with methyl modifying enzymes. Also provided are pharmaceutical compositions comprising the novel compounds of Formula (I), pharmaceutically acceptable salts thereof, and methods for their use in treating one or more diseases, disorders or conditions, associated with methyl modifying enzymes.

Pyrano[3,2-c] julolidin-2-ones: A novel class of fluorescent probes for ratiometric detection and imaging of Hg2+ in live cancer cells

Jha, Ajay Kumar,Umar, Shahida,Arya, Rakesh Kumar,Datta, Dipak,Goel, Atul

, p. 4934 - 4940 (2016/07/26)

A novel pyrano[3,2-c]julolidin-2-one based fluorescent molecular rotor PYJO4 has been designed and developed for selective ratiometric detection, quantification and imaging of intracellular Hg2+ in live cells. The probe operates via a Twisted Intramolecular Charge Transfer (TICT) mechanism and exhibits high selectivity and sensitivity up to 1.14 ppb. PYJO4 coated test strips can be used to detect mercury ions in contaminated water.

Novel pyranopyrandione compounds or pharmaceutically acceptable salts thereof, process for preparing thereof and pharmaceutical composition comprising the same for treating disease derived from allergic inflammatory response

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Paragraph 0070-0074, (2017/05/11)

The present invention relates to novel pyranopyrandione compounds or pharmaceutically acceptable salts thereof, preparing methods thereof, and pharmaceutical compositions comprising the same for treating diseases resulting from allergic inflammatory respo

Design and synthesis of potent N-phenylpyrimidine derivatives for the treatment of skin cancer

Chaube, Udit J.,Vyas, Vivek K.,Bhatt, Hardik G.

, p. 10285 - 10297 (2016/02/09)

The development of novel synthetic compounds for the treatment of skin cancer is much needed, as there is a sudden rise in the incidence of skin cancer throughout the world and the available chemotherapy is facing problems of resistance. Hence, present re

New fluoranthene FLUN-550 as a fluorescent probe for selective staining and quantification of intracellular lipid droplets

Goel, Atul,Sharma, Ashutosh,Kathuria, Manoj,Bhattacharjee, Arindam,Verma, Ashwni,Mishra, Prabhat R.,Nazir, Aamir,Mitra, Kalyan

supporting information, p. 756 - 759 (2014/03/21)

A new class of live cell permeant, nontoxic fluoranthene-based fluorescent probe (FLUN-550) having a high Stokes shift in aqueous medium has been discovered. It showed selective staining of lipid droplets (LDs, dynamic cytoplasmic organelles) at a low con

A regioselective synthesis of 2,6-diarylpyridines

Maurya, Hardesh K.,Vasudev, Prema G.,Gupta, Atul

, p. 12955 - 12962 (2013/08/23)

A regioselective synthesis of 2,6-diarylpyridines through base (sodium hydroxide in DMSO) catalyzed ring transformation of suitably functionalized 2H-pyran-2-ones with benzamide has been delineated. However, similar reaction of 2H-pyran-2-ones with benzam

Synthesis and antiviral bioactivities of 2-cyano-3-substitutedamino(phenyl) methylphosphonylacrylates (Acrylamides) containing alkoxyethyl moieties

Yang, Jia-Qiang,Song, Bao-An,Bhadury, Pinaki S.,Chen, Zhuo,Yang, Song,Xue-Jian, Cai,Hu, De-Yu,Xue, Wei

experimental part, p. 2730 - 2735 (2011/07/31)

An efficient reaction under microwave irradiation has been developed for the synthesis of a series of novel 2-cyano-3-substituted-amino(phenyl) methylphosphonylacrylates (acrylamides) II. The products obtained in shorter reaction time with moderate yields are fully characterized by elemental analysis, IR, 1H, 13C, and 31P NMR spectral data. The role of introducing various substituents and the effect of incorporating a-aminophosphonates with an alkoxyethyl moiety into the parent cyanoacrylate (acrylamide) structure are investigated. Among the studied compounds, both II-17 and II-24 displayed good in vivo curative, protection, and inactivation effects, which were comparable to those of the commercial reference ningnanmycin (inhibitory rates of 58.8, 60.2, 78.9% and 60.0, 58.9, 85.5%, respectively, at 500 mg/L against TMV). To the best of the authors' knowledge, this is the first report on the synthesis and antiviral activity of the title compounds II.

Donor-acceptor 9-uncapped fluorenes and fluorenones as stable blue light emitters

Goel, Atul,Chaurasia, Sumit,Dixit, Manish,Kumar, Vijay,Prakash, Sattey,Jena, Bijayalaxmi,Verma, Jai K.,Jain, Mayank,Anand,Manoharan, S. Sundar

supporting information; experimental part, p. 1289 - 1292 (2009/08/08)

The "green emission defect" (GED) produced by fluorenones has significantly retarded the commercial scope of fluorene-based B-OLEDs. In this paper, for the first time, it is demonstrated that the "green light" emitting fluorenones 7 can be converted to "b

Synthesis and antiviral activities of cyanoacrylate derivatives containing an α-aminophosphonate moiety

Long, Ning,Cai, Xue-Jian,Song, Bao-An,Yang, Song,Chen, Zhuo,Bhadury, Pinaki S.,Hu, De-Yu,Jin, Lin-Hong,Xue, Wei

scheme or table, p. 5242 - 5246 (2010/04/06)

Target compounds 8 were obtained by the reaction of alkyl 2-cyano-3,3-dimethylthioacrylate or cyarylamide (7a-7e) and α- aminobenzylphosphonate (5a-5e) under reflux condition using ethanol as solvent. Their structures were clearly verified by spectroscopic data (IR and 1H, 13C, and 31P NMR) and elemental analysis. These compounds were shown to be antivirally active in the bioassay. It was found that title compounds 8d and 8e had the same inactivation effect against tobacco mosaic virus (EC50 = 55.5 and 55.3 μg/mL) as the commercial product ningnanmycin (EC50 = 50.9 μg/mL). To the best of our knowledge, this is the first report on the synthesis and antiviral activity of cyanoacrylate derivatives containing an α-aminophosphonate moiety.

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