3490-92-4

Basic information

• Product Name: METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE
• Synonyms: AURORA KA-6539;METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE;METHYL 3,3-BIS(METHYLTHIO)-2-CYANOACRYLATE;ethyl2-cyano-3,3-di(methylthio)acrylate;METHYL 2-CYANO-3,3-BIS(METHYLTHIO)ACRYLATE;2-Cyano-3,3-bis-methylsulfanyl-acrylic acid methyl ester;2-Propenoic acid,2-cyano-3,3-bis(methylthio)-, methyl ester;Methyl 3,3-bis(methylsulphanyl)-2-cyanoprop-2-enoate
• CAS NO: 3490-92-4
• Molecular Formula: C₇H₉NO₂S₂
• Molecular Weight: 203.28
• Mol File: 3490-92-4.mol
• Article Data: 15

Chemical Properties

• Melting Point: 85 °C
• Boiling Point: 300.765 °C at 760 mmHg
• Flash Point: 135.698 °C
• Appearance: /
• Density: 1.254 g/cm³
• Vapor Pressure: 0.0011mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE(3490-92-4)
• EPA Substance Registry System: METHYL 2-CYANO-3,3-DI(METHYLTHIO)ACRYLATE(3490-92-4)

Safety Data

• HazardClass: IRRITANT
• Hazardous Substances Data: 3490-92-4(Hazardous Substances Data)

Usage

General Description

Methyl 2-cyano-3,3-di(methylthio)acrylate is a chemical compound with the molecular formula C8H11NO2S2. It is a clear, colorless liquid with a pungent odor. This chemical is commonly used in the synthesis of various organic compounds and polymers. It is also used in the production of adhesives, coatings, and other industrial products. Methyl 2-cyano-3,3-di(methylthio)acrylate is known to be a skin and eye irritant and may cause respiratory irritation if inhaled. It should be handled and stored with care to prevent exposure and potential hazards.

InChI:InChI=1/C7H9NO2S2/c1-10-6(9)5(4-8)7(11-2)12-3/h1-3H3

Upstream product

• 75-15-0 carbon disulfide 
• 105-34-0 methyl 2-cyanoacetate 
• 74-88-4 methyl iodide 
• 77-78-1 dimethyl sulfate 
• 74598-57-5 2-cyano-3,3-dimercapto-2-propenoic acid methyl ester 
• 624-92-0 Dimethyldisulphide 
• 119491-91-7 potassium 2-cyano-3-methoxy-3-oxoprop-1-ene-1,1-bis(thiolate) 

Downstream Products

• 17823-64-2 methyl 2-cyano-3-(methylthio)-3-(phenylamino)acrylate 
• 92964-02-8 2-Methylmercapto-3-acetyl-3-benzoyl-1-cyan-crotonsaeure-methylester 
• 116931-43-2 C₂₂H₁₅N₃O₂S 
• 87693-85-4 methyl 2-cyano-3-methylthio-3-N-p-methoxybenzoylaminoacrylate 
• 118996-51-3 (Z)-2-Cyano-3-(4-methoxy-benzoylamino)-3-methylsulfanyl-acrylic acid methyl ester 
• 87693-86-5 methyl 2-cyano-3-methylthio-3-N-styrylcarbonylaminoacrylate 
• 87693-86-5 (Z)-2-Cyano-3-methylsulfanyl-3-[(E)-(3-phenyl-acryloyl)amino]-acrylic acid methyl ester 
• 65657-69-4 6-(4-chloro-styryl)-4-methylsulfanyl-2-oxo-2H-pyran-3-carbonitrile 
• 108675-26-9 1-Benzyl-1-methyl-5-(methylthio)-3-oxo-3H-1λ⁶,2,6-thiadiazin-4-carbonitril 
• 108675-27-0 1-Benzyl-1-ethyl-5-(methylthio)-3-oxo-3H-1λ⁶,2,6-thiadiazin-4-carbonitril 
• 16071-28-6 3,4-dihydro-6-methymercapto-4-oxopyrimidine-5-carbonitrile 
• 15908-63-1 3,4-dihydro-2-methyl-6-methylmercapto-4-oxopyrimidine-5-carbonitrile 
• 15908-64-2 3,4-dihydro-6-methymercapto-4-oxo-2-phenylpyrimidine-5-carbonitrile 
• 131890-63-6 5-Amino-1-[5-cyano-4-(3-methoxy-phenyl)-1-methyl-6-oxo-1,6-dihydro-pyrimidin-2-yl]-3-methylsulfanyl-1H-pyrazole-4-carboxylic acid methyl ester 

Relevant articles and documents

HEADGROUP LIPID COMPOUNDS AND COMPOSITIONS FOR INTRACELLULAR DELIVERY OF THERAPEUTIC AGENTS

The application relates to lipids of Formula (A-1) and compositions involving the same. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) include such a lipid as well as additional lipids such as phospholipids, structural lipids, and PEG lipids. Lipid nanoparticles (e.g., empty LNPs or loaded LNPs) further including therapeutic and/ or prophylactics such as RNA are useful in the delivery of therapeutic and/or prophylactics to mammalian cells or organs to, for example, regulate polypeptide, protein, or gene expression.

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Design and synthesis of potent N-phenylpyrimidine derivatives for the treatment of skin cancer

The development of novel synthetic compounds for the treatment of skin cancer is much needed, as there is a sudden rise in the incidence of skin cancer throughout the world and the available chemotherapy is facing problems of resistance. Hence, present re