178243-14-6

Basic information

• Product Name: 2-(1-pyrrolidinyl-1-cyclohexyl)ethylamine
• Synonyms: 2-(1-pyrrolidinyl-1-cyclohexyl)ethylamine
• CAS NO: 178243-14-6
• Molecular Weight: 196.336
• Mol File: 178243-14-6.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2-(1-pyrrolidinyl-1-cyclohexyl)ethylamine(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(1-pyrrolidinyl-1-cyclohexyl)ethylamine(178243-14-6)
• EPA Substance Registry System: 2-(1-pyrrolidinyl-1-cyclohexyl)ethylamine(178243-14-6)

Safety Data

• Hazardous Substances Data: 178243-14-6(Hazardous Substances Data)

Upstream product

• 24571-98-0 1-aza-spiro[3.5]nonan-2-one 
• 1192-37-6 methylenecyclohexane 
• 178242-64-3 (1-amino-cyclohexyl)-acetic acid methyl ester 
• 4435-18-1 2-cyclohexylideneacetonitrile 
• 204651-45-6 2-(1-amino-1-cyclohexyl)acetonitrile 

Relevant articles and documents

Synthesis of novel restricted diamines; 2-(1-aminocycloalkan-1- yl)ethylamines

Novel restricted diamines, 2-(1-aminocycloalkan-1-yl)ethylamines 1,were prepared by using Michael addition of ethyl cyclohexylideneacetate 2 and cycloalkylideneacetonitriles 7 with amines. In Michael addition, ester 2 needed high reaction temperature and gave several products, whereas 7 reacted smoothly and gave 2-(1-amino-1-cyclohexyl)acetonitriles 8 in good yield (NH3 85%, MeNH2 89%, EtNH2 80%) and were easily convened to diamines 1.