17832-16-5

Basic information

• Product Name: TRIALLYL 1,3,5-BENZENETRICARBOXYLATE
• Synonyms: 1,3,5-BENZENETRICARBOXYLIC ACID TRIALLYL ESTER;TRIMESIC ACID TRIALLYL ESTER;TRIALLYL 1,3,5-BENZENETRICARBOXYLATE;TRIALLYL TRIMESATE;triallyl benzene-1,3,5-tricarboxylate;TRIALLYL 1,3,5-BENZENETRICARBOXYLATE, 98 %;1,3,5-Benzenetricarboxylic acid tris(2-propenyl) ester;1,3,5-Benzenetricarboxylic acid triallyl ester,98%
• CAS NO: 17832-16-5
• Molecular Formula: C₁₈H₁₈O₆
• Molecular Weight: 330.33
• EINECS: 241-791-4
• Mol File: 17832-16-5.mol
• Article Data: 3

Chemical Properties

• Melting Point: 31-34 °C(lit.)
• Boiling Point: 175-190 °C0.1 mm Hg(lit.)
• Flash Point: >230 °F
• Appearance: Light yellow/Liquid or Low Melting Solid
• Density: 1.16
• Vapor Pressure: 2.01E-08mmHg at 25°C
• Refractive Index: 1.5200 (estimate)
• Storage Temp.: 2-8°C
• CAS DataBase Reference: TRIALLYL 1,3,5-BENZENETRICARBOXYLATE(CAS DataBase Reference)
• NIST Chemistry Reference: TRIALLYL 1,3,5-BENZENETRICARBOXYLATE(17832-16-5)
• EPA Substance Registry System: TRIALLYL 1,3,5-BENZENETRICARBOXYLATE(17832-16-5)

Safety Data

• Safety Statements: 23-24/25
• WGK Germany: 3
• Hazardous Substances Data: 17832-16-5(Hazardous Substances Data)

Usage

Chemical Properties

light yellow liquid or low melting solid

InChI:InChI=1/C18H18O6/c1-4-7-22-16(19)13-10-14(17(20)23-8-5-2)12-15(11-13)18(21)24-9-6-3/h4-6,10-12H,1-3,7-9H2

Upstream product

• 554-95-0 benzene-1,3,5-tricarboxylic acid 
• 107-18-6 allyl alcohol 
• 2672-58-4 1,3,5-tris-(methoxycarbonyl)benzene 
• 107-05-1 3-chloroprop-1-ene 

Downstream Products

• 1448710-24-4 diallyl trimesic acid 
• 7176-19-4 1,3,5-triglycidyl benzenetricarboxylate 

Relevant articles and documents

METHOD FOR PRODUCING CURING AGENT OF COATING AND ITS APPLICATION ON COATING

The curing agent for coatings includes at least 1,3,5-triglycidyl benzenetricarboxylate and 1,3,5-diglycidyl benzenetricarboxylate. To produce the curing agent, 1,3,5-benzenetricarboxylic acid reacts with a base and chloropropene to produce triallyl benzene-1,3,5-tricarboxylate. Then the triallyl benzene-1,3,5-tricarboxylate reacts with a surfactant, hydrogen peroxide and a catalyst to produce 1,3,5-triglycidyl benzenetricarboxylate and/or 1,3,5-diglycidyl benzenetricarboxylate. The 1,3,5-triglycidyl benzenetricarboxylate can be applied to coatings as a curing agent.

Screening bicyclic peptide libraries for protein-protein interaction inhibitors: Discovery of a tumor necrosis factor-α Antagonist

Protein-protein interactions represent a new class of exciting but challenging drug targets, because their large, flat binding sites lack well-defined pockets for small molecules to bind. We report here a methodology for chemical synthesis and screening of large combinatorial libraries of bicyclic peptides displayed on rigid small-molecule scaffolds. With planar trimesic acid as the scaffold, the resulting bicyclic peptides are effective for binding to protein surfaces such as the interfaces of protein-protein interactions. Screening of a bicyclic peptide library against tumor necrosis factor-α (TNFα) identified a potent antagonist that inhibits the TNFα-TNFα receptor interaction and protects cells from TNFα-induced cell death. Bicyclic peptides of this type may provide a general solution for inhibition of protein-protein interactions.