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Upstream product

• 104-94-9 4-methoxy-aniline 
• 36746-06-2 ethyl 4-chloro-6-methyl-2-phenyl-pyrimidine-5-carboxylate 
• 23155-55-7 ethyl 4-mercapto-6-methyl-2-phenyl-5-pyrimidinecarboxylate 

Relevant academic research and scientific papers

Synthesis and antibacterial properties of pyrimidine derivatives

In this study, a series of syntheses was conducted on the pyrimidine system, obtaining bisulfite carboxyl derivatives 4 and hydroxy derivatives 5. In addition, a series of syntheses were carried out as a result of which both alkyl and aromatic amines were

Some reactions with ethyl 4-(mercapto/ chloro)-6-methyl-2-phenylpyrimidine-5-carboxylate

Michael adducts (2a,b), transesters, 4a,b and/or chloropyrimidine (5) have been synthesized from 4-mercaptopyrimidine (1). Compound 5 on reaction with ethyl glycinate, arylamines, 2-aminopyridine, ammonium acetate, acid hydrazide, hydrazine, and/or benzilmonohydrazone gives pyrrolopyrimidine (8), 4-arylaminopyrimidines (9a,b), pyridylaminopyrimidine (11), 4-aminopyrimidine (13), 4-aroylhydrazinopyrimidine (15a,b), 1,2-bis(substituted phenylpyrimidine-4-yl)hydrazine (19) and/or pyrimidopyridazine (20), respectively. ? Present address: Chemistry Department, Faculty of Science, Cairo University, AR Egypt.