178421-21-1 Usage
General Description
Ethyl 6-chloro-5-methylpicolinate is a chemical compound with the molecular formula C8H9NO2Cl. It is a derivative of picolinic acid and is commonly used in organic synthesis as a building block for the production of pharmaceuticals and agrochemicals. The compound contains a chlorine atom and a methyl group attached to a pyridine ring, making it a valuable intermediate in the development of various compounds with biological activity. Ethyl 6-chloro-5-methylpicolinate is known for its versatile reactivity and is used as a key starting material in the synthesis of pyridine-based heterocycles, which have potential applications in medicinal chemistry research.
Check Digit Verification of cas no
The CAS Registry Mumber 178421-21-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,4,2 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 178421-21:
(8*1)+(7*7)+(6*8)+(5*4)+(4*2)+(3*1)+(2*2)+(1*1)=141
141 % 10 = 1
So 178421-21-1 is a valid CAS Registry Number.
178421-21-1Relevant articles and documents
A new pathway to substituted 6-chloro-2-pyridinecarboxylic acid derivatives from the reaction of 4,6-dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones with nucleophiles
Dubois, Kristof J.,Hoornaert, Georges J.
, p. 6997 - 7002 (1996)
Reaction of alcohols or amines with 4,6-dichloro-2-oxa-5-azabicyclo[2.2.2]oct-5-en-3-ones gives direct conversion into (3,(4,))5-substituted 6-chloro-2-pyridinecarboxylic acid derivatives via selective lactone cleavage followed by rapid elimination of HCl and H2O in the presence of DBU. Copyright
