178424-16-3Relevant academic research and scientific papers
Bone targeted drugs 2. Synthesis of estrogens with hydroxyapatite affinity
Willson, Timothy M.,Henke, Brad R.,Momtahen, Tanya M.,Garrison, Deanna T.,Moore, Linda B.,Geddie, Nora G.,Baer, Philip G.
, p. 1047 - 1050 (1996)
The utility of the bone targeting 4-carboxy-3-hydroxy-1,2-pyrazole heterocycle was tested by the synthesis of hybrids with the non-steroidal estrogen hexestrol. Compounds 1 and 2 demonstrated significant hydroxyapatite affinity, while maintaining weak estrogenic activity in whole cell assays. Copyright
Vitamin D derivatives with cyclic substructures in the side chains, process and intermediate products for their production, and the use for the production of pharmaceutical agents
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, (2008/06/13)
The invention relates to vitamin D derivatives of general formula I, process for their production, intermediate products of the process as well as the use for the production of pharmaceutical agents.
