178425-35-9Relevant academic research and scientific papers
Synthesis of an AZT-HEPT hybrid and homologous AzddU derivatives
Larsen, Erik,Danel, Krzysztof,Vaaben, Gitte B.,El-Emam, Ali A.,Pedersen, Erik B.,Nielsen, Claus
, p. 417 - 421 (2007/10/03)
3′-Azido-2′,3′-dideoxyuridines 6 and their corresponding α anomers 5 were syrthesizes by condensation of silylated 6-alkyl and 5,6-dialkyl substituted uracils 2 with methyl 3-azido-5-O-tert-butyldiphenylsilyl-2,3-dideoxy-α,β-D-erythro- pentofuranoside (4). Compounds 5 and 6 were treated with tetrabutylammonium fluoride to obtain the deprotected nucleosides 7 and 8, respectively. Acta Chemica Scandinavica 1996.
