178449-39-3

Upstream product

• 178449-34-8 (2S,3S,3aS,12bR,12cR)-3-Hydroxy-7-oxo-2-phenylselanyl-2,3,4,5,12b,12c-hexahydro-1H,7H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-3a-carboxylic acid benzyl ester 
• 178449-43-9 (1aR,6aS,6bS)-4-(6-Iodo-benzo[1,3]dioxole-5-carbonyl)-1a,2,4,5,6,6b-hexahydro-1-oxa-4-aza-cyclopropa[e]indene-6a-carboxylic acid benzyl ester 
• 151071-70-4 (2'S,6R)-1-methoxy-6-(2-azidoethyl)-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene 
• 151071-62-4 (2'S,6R)-1-methoxy-6-(2-hydroxyethyl)-6-<<2'-(methoxymethyl)pyrrolidinyl>carbonyl>-1,4-cyclohexadiene 
• 108-24-7 acetic anhydride 
• 178449-36-0 (3R,3aS,12bR,12cR)-3-Hydroxy-7-oxo-4,5,12b,12c-tetrahydro-3H,7H-[1,3]dioxolo[4,5-j]pyrrolo[3,2,1-de]phenanthridine-3a-carboxylic acid benzyl ester 
• 178449-42-8 (1R,8R,11R)-11-Iodo-4-(6-iodo-benzo[1,3]dioxole-5-carbonyl)-9-oxa-4-aza-tricyclo[6.2.1.0^1,5]undec-5-en-10-one 
• 178449-29-1 (R)-2-(2-Azido-ethyl)-2-((S)-2-methoxymethyl-pyrrolidine-1-carbonyl)-cyclohex-3-enone 
• 178449-30-4 (1R,5R,8R)-1-(2-Azido-ethyl)-8-iodo-6-oxa-bicyclo[3.2.1]octane-2,7-dione 
• 151071-66-8 (2R,3S,12S,15R,16R)-2,3-epoxy-12-(benzyloxycarbonyl)-9,10-galanthan-7-one 
• 178449-44-0 (3aS,4S,5R)-N-(piperonyloyl)-4,5-epoxy-5,6-dihydro-4H-3a-(benzyloxycarbonyl)indoline 

Downstream Products

• 178449-40-6 (1R,2R,3R,12S,15R,16R)-1-acetyloxy-2,3-epoxy-12-(benzyloxycarbonyl)-9,10-[methylenebis(oxy)]galanthan-7-one 

Relevant academic research and scientific papers

The first asymmetric total syntheses of (+)-lycorine and (+)-1-deoxylycorine

The first asymmetric total syntheses of (+)-1-deoxylycorine (2a) and (+)-lycorine (2b), the unnatural enantiomer of lycorine (1), are described. Construction of lactam 12, a key intermediate in the synthesis of both 2a and 2b, began by Birch reduction-alk