17851-38-6Relevant academic research and scientific papers
Photoredox/Nickel Dual Catalysis for the C(sp3)–C(sp3) Cross-Coupling of Alkylsilicates with Alkyl Halides
Lévêque, Christophe,Corcé, Vincent,Chenneberg, Ludwig,Ollivier, Cyril,Fensterbank, Louis
supporting information, p. 2118 - 2121 (2017/04/24)
Alkylsilicates were engaged under photoredox/nickel dual catalysis conditions with alkyl halides for the first time. The C(sp3)–C(sp3) cross-coupling products were obtained in moderate yields and were accompanied by the homocoupling
Nickel-catalyzed cross-coupling between functionalized primary or secondary alkylzinc halides and primary alkyl halides
Jensen, Anne Eeg,Knochel, Paul
, p. 79 - 85 (2007/10/03)
In the presence of Bu4NI (3 equiv) and 4-fluorostyrene (20 mol %), unreactive primary and secondary alkylzinc iodides undergo nickel-catalyzed cross-couplings with various primary alkyl iodides or bromides. More reactive secondary dialkylzincs and the mixed zinc organometallics RZnTMSM undergo the cross-coupling reaction in the absence of Bu4NI. The bicyclic secondary diorganozinc 6 prepared via boron-zinc exchange reacts with high retention of configuration. Free NH-groups are tolerated in the cross-coupling allowing the synthesis of aminated products.
Cross-Coupling between Functionalized Alkylcopper Reagents and Functionalyzed Alkyl Halides
Tucker, Charles E.,Knochel, Paul
, p. 4781 - 4782 (2007/10/02)
Functionalized dialkylzincs treated with Me2Cu(CN)(MgCl)2 in DMPU undergo highly chemoselective cross-coupling reactions with functionalized alkyl iodides or benzylic bromides providing polyfunctional products in good to excellent yields.
