58509-74-3Relevant academic research and scientific papers
A short, gram-scale synthesis of 2,5-disubstituted furans
Chang, Stanley,Desai, Saheena,Leznoff, Daniel B.,Merbouh, Nabyl,Britton, Robert
supporting information, p. 3219 - 3222 (2013/07/05)
A modified Feist-Benary furan synthesis has been developed that involves a lithium aldol reaction between a methyl ketone and an α-chloroaldehyde followed by a thermally induced tetrahydrofuran formation/dehydration sequence and affords 2,5-disubstituted
A metathesis-based approach to the synthesis of furans
Donohoe, Timothy J.,Fishlock, Lisa P.,Lacy, Adam R.,Procopiou, Panayiotis A.
, p. 953 - 956 (2007/10/03)
(Chemical Equation Presented) The enol ether-olefin ring-closing metathesis reaction has been employed to generate 2,3-dihydrofurans that are equipped with a leaving group. These substrates are at the correct oxidation state to undergo an acid-catalyzed a
A mild synthesis of substituted furans from -γ-hydroxy-α,β-unsaturated ketones
Sammond, Douglas M.,Sammakia, Tarek
, p. 6065 - 6068 (2007/10/03)
The acid-catalyzed cyclodehydration of (Z)- and (E)-γ-hydroxy-α,β-unsaturated ketones to furans is described. In the case of E olefins, photochemical trans- to cis-olefin isomerization was found to accelerate the reaction.
Intramolecular hydride shift in some noncyclic isopropyl ketols
Warnhoff, E. W.,Wong, Margaret Y. H.,Raman, P. Sundara
, p. 688 - 696 (2007/10/02)
The acyclic ketols 711 and 812 have been synthesized by a Reformatsky sequence.Each ketol undergoes intramolecular hydride transfer when refluxed in KOH-H2O-t-BuOH solution.When the procedure was applied to the synthesis of 34, hydride transfer ocur
