1786-03-4

Basic information

• Product Name: 2-naphthalen-1-ylindene-1,3-dione
• Synonyms: 2-naphthalen-1-ylindene-1,3-dione;1,2-naphthyl-1,3-indandione;2-(1-Naphtyl)-1H-indene-1,3(2H)-dione;2-(1-Naphtyl)indane-1,3-dione;NID;Radione
• CAS NO: 1786-03-4
• Molecular Formula: C19H12O2
• Molecular Weight: 272.3
• Mol File: 1786-03-4.mol
• Article Data: 7

Chemical Properties

• Boiling Point: 501.2°Cat760mmHg
• Flash Point: 185.3°C
• Appearance: /
• Density: 1.297g/cm³
• Vapor Pressure: 3.54E-10mmHg at 25°C
• Refractive Index: 1.698
• CAS DataBase Reference: 2-naphthalen-1-ylindene-1,3-dione(CAS DataBase Reference)
• NIST Chemistry Reference: 2-naphthalen-1-ylindene-1,3-dione(1786-03-4)
• EPA Substance Registry System: 2-naphthalen-1-ylindene-1,3-dione(1786-03-4)

Safety Data

• RIDADR: 3027
• HazardClass: 6.1(b)
• PackingGroup: III
• Hazardous Substances Data: 1786-03-4(Hazardous Substances Data)

Usage

Uses

Naphthylin is a novel indanedione with anticoagulation, antitumor, and hypolipidemic activity.

InChI:InChI=1/C19H12O2/c20-18-15-9-3-4-10-16(15)19(21)17(18)14-11-5-7-12-6-1-2-8-13(12)14/h1-11,17H

Upstream product

• 34883-80-2 3-naphthalen-1-ylmethylene-3H-isobenzofuran-1-one 
• 87-41-2 2-benzofuran-1(3H)-one 
• 66-77-3 1-naphthaldehyde 
• 85-44-9 phthalic anhydride 
• 86-87-3 naphth-1-yl acetic acid 
• 606-23-5 1H-indene-1,3(2H)-dione 
• 99747-74-7 1-naphthyl triflate 
• 90-15-3 α-naphthol 

Downstream Products

• 62345-42-0 2-Naphthalen-1-yl-3-(4-nitro-benzyloxy)-inden-1-one 
• 62345-32-8 2-(1-Naphthyl)-2-(p-nitrobenzyl)-1,3-indandion 
• 62345-48-6 3-(3-Iodo-benzyloxy)-2-naphthalen-1-yl-inden-1-one 
• 62345-34-0 2-(1-Naphthyl)-2-(m-iod-benzyl)-1,3-indandion 
• 62345-46-4 3-(4-Methyl-benzyloxy)-2-naphthalen-1-yl-inden-1-one 
• 62345-40-8 2-(1-Naphthyl)-2-(p-methyl-benzyl)-1,3-indandion 
• 34225-30-4 1-Benzyloxy-2-(1-naphthyl)-1-inden-3-on 
• 62345-50-0 3-(4-Methoxy-benzyloxy)-2-naphthalen-1-yl-inden-1-one 
• 62345-41-9 2-(4-Methoxy-benzyl)-2-naphthalen-1-yl-indan-1,3-dione 
• 34225-26-8 2-(1-Naphthyl)-2-(benzyl)-1,3-indandion 
• 62345-45-3 3-(4-Iodo-benzyloxy)-2-naphthalen-1-yl-inden-1-one 
• 62345-37-3 2-(1-Naphthyl)-2-(p-iod-benzyl)-1,3-indandion 
• 62345-49-7 3-(3-Methyl-benzyloxy)-2-naphthalen-1-yl-inden-1-one 
• 62345-39-5 2-(1-Naphthyl)-2-(m-methyl-benzyl)-1,3-indandion 

Relevant articles and documents

INDANONE AND INDANDIONE DERIVATIVES AND HETEROCYCLIC ANALOGS

The invention relates to indanone/indandione derivatives and heterocyclic analogs of Formula (I) wherein Ar1, A, B, L1, Y, Z, and (R1)n n are as described in the description; to pharmaceutically acceptable salts thereof, and to the use of such compounds as medicaments, especially as NPS receptor antagonists.

Synthesis and pharmacological properties of sulfur derivatives of indane-1,3-dione

Synthesis of sulfur derivatives of indane-1,3-dione, VIIb-c, VIIIa-b, IX and X is described. Results of a preliminary pharmacological screening of six compounds [VIIb, VIII, VIIIb, IX, X and XI] are presented.