178603-05-9

Basic information

• Product Name: Bicyclo[2.2.1]heptan-1-amine, 3,3-dimethyl-2-methylene-, (1R,4R)- (9CI)
• Synonyms: Bicyclo[2.2.1]heptan-1-amine, 3,3-dimethyl-2-methylene-, (1R,4R)- (9CI)
• CAS NO: 178603-05-9
• Molecular Formula: C10H17N
• Molecular Weight: 151.24868
• Product Categories: CYCLOPENTANE
• Mol File: 178603-05-9.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Bicyclo[2.2.1]heptan-1-amine, 3,3-dimethyl-2-methylene-, (1R,4R)- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Bicyclo[2.2.1]heptan-1-amine, 3,3-dimethyl-2-methylene-, (1R,4R)- (9CI)(178603-05-9)
• EPA Substance Registry System: Bicyclo[2.2.1]heptan-1-amine, 3,3-dimethyl-2-methylene-, (1R,4R)- (9CI)(178603-05-9)

Safety Data

• Hazardous Substances Data: 178603-05-9(Hazardous Substances Data)

Upstream product

• 140147-15-5 (1R)-3,3-dimethyl-2-methylenenorborn-1-yl triflate 
• 464-49-3 (1R,4R)-1,7,7-trimethylbicyclo[2.2.1]heptan-2-one 
• 178603-04-8 N-((1R,4R)-3,3-Dimethyl-2-methylene-bicyclo[2.2.1]hept-1-yl)-acetamide 
• 10367-38-1 2-bromo-2-nitro-bornane 
• 13559-66-5 (+/-)-camphor oxime 
• 6244-05-9 3,3-dimethyl-2-methylene-1-nitro-norbornane 

Downstream Products

• 22780-14-9 (1R)-3,3-dimethyl-2-methylenenorbornan-1-ol 
• 178603-06-0 (1R)-3,3-dimethyl-2-oxo-1-norbornylamine 

Relevant articles and documents

Synthesis of homochiral 3-substituted cyclopentanones from 2-norbornanones

The cleavage of the C1-C2 bond in norbornate derivatives is accomplished by base-promoted hydrolysis of α-nitroketones, periodate oxidation or Beckmann fragmentation of suitable precursors prepared from the 2-norbornanones 1. These reactions are the basis for the synthesis of the 3-substituted homochiral cyclopentanones 6, 10 or 15.