178614-60-3

Upstream product

• 178614-59-0 [2-hydroxymethyl-4-(4-methylsulfanylphenyl)-5-phenylthiophen-3-yl] acetic acid 
• 76-26-6 camphor-10-sulfonic acid 

Downstream Products

• 178614-32-9 2-Phenyl-3-(4-(methylsulfonyl)phenyl)-4,7-dihydro-thieno[2,3-c]pyran-5-one 

Relevant academic research and scientific papers

Diaryl bicyclic heterocycles as inhibitors of cyclooxygenase-2

The invention encompasses the novel compound of Formula I as well as a method of treating cyclooxygenase-2 mediated diseases comprising administration to a patient in need of such treatment of a non-toxic therapeutically effective amount of a compound of Formula I. STR1 The invention also encompasses certain pharmaceutical compositions for treatment of cyclooxygenase-2 mediated diseases comprising compounds of Formula I.