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Usage

Uses

Used in Pharmaceutical Industry:
D3-MSA is used as a chiral auxiliary in the production of chiral pharmaceuticals for their specific therapeutic effects. Its unique structure allows for the creation of enantiomerically pure compounds, which is crucial in the development of effective and safe medications.
Used in Agrochemical Industry:
In the agrochemical industry, D3-MSA is used as a precursor to develop crop protection products, such as pesticides and herbicides. Its role in creating chiral compounds aids in enhancing the selectivity and efficiency of these products, reducing potential harm to non-target organisms and the environment.
Used in Research and Development:
D3-MSA is also employed in research and development, particularly in the synthesis of complex organic molecules. Its versatility as a chiral auxiliary makes it a valuable tool for chemists working on the design and synthesis of novel compounds with potential applications in various fields.

Upstream product

• 736109-58-3 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one 

Downstream Products

• 367522-55-2 7,7-dimethyl-2,3-dioxo-bicyclo[2.2.1]heptane-4-methanesulfonic acid 
• 165806-94-0 N-[(4-fluorophenyl)[(4-methylphenyl)sulfonyl]methyl]formamide 
• 10413-17-9 6-phenyltetrahydropyran-2-one 
• 114214-50-5 3-hydroxy-4-methoxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 183540-37-6 1-Benzyl-3-(R)-tetrahydropyranyloxypyrrolidine 
• 103185-70-2 ethyl 6-(3,5,6-trimethyl-1,4-benzoquinon-2-yl)-6-(2-thienyl)hexanoate 
• 103185-89-3 6-(4-methoxyphenyl)-6-(3-methyl-1,4-naphthoquinon-2-yl)hexanoic acid 
• 71347-90-5 N,N'-(3-oxa-pentane-1,5-diyl)-bis-carbamic acid dibenzyl ester 
• 3539-40-0 ethyl 2-((tetrahydro-2H-pyran-2-yl)oxy)propanoate 
• 186664-64-2 cis-6-(Ethoxy)-3a,8a-di-(hydro)-3H-8-oxacyclopenta[a]indene-5-ol 
• 909279-85-2 clopidogrel camphorsulfonate 

Relevant academic research and scientific papers

Identification of small molecule sulfonic acids as ecto-5'-nucleotidase inhibitors

Ecto-5'-Nucleotidase inhibitors have great potential as anti-tumor agents. We have investigated biochemical properties of human and rat ecto-5'-Nucleotidases and characterized 19 small molecule sulfonic acid derivatives as potential inhibitors of ecto-5'-Nucleotidases. We identified 11 potent inhibitors of human and rat ecto-5'-Nucleotidases and checked their selectivity. Compound 10 (Sodium 2,4-dinitrobenzenesulfonate) with Ki value of 0.66 μM and 19 (N-(4- sulfamoylphenylcarbamothioyl) pivalamide) with Ki value of 0.78 μM were identified as the most potent inhibitors for human and rat ecto-5'-Nucleotidase, respectively. The present compounds have low molecular weights, water solubility and equal potency as compared to the reported inhibitors.

Polymorphic clopidogrel hydrogenesulphate form

Novel orthorombic polymorph of clopidogrel hydrogen sulfate or hydrogen sulfate of methyl (+)-(S)-α-(2-chlorophenyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine-5-acetate and a process for its preparation.

Dibenzonaphthyrones

Dibenzonaphthyrone of formula (I) wherein A1and A2independently of each other are unsubstituted or mono- to tetra-substituted o-C6-C18arylene, with the proviso that formula (I) does not represent a dibenzonaphthyrone of the formula The invention further relates to processes for the preparation thereof, to the use thereof for colouring/pigmenting high-molecular-weight organic material and to substance compositions comprising dibenzonaphthyrones.

Process for the preparation of D(-)αphenylglycine

The invention provides a process for the preparation of D(-)αphenylglycine by resolution of DLαphenylglycine by means of D(+)camphorsulfonic acid. The present process enables the preparation of D(-)αphenylglycine at a minimum loss of the very expensive starting materials, such as DLαphenylglycine and D(+)camphorsulfonic acid. The salts produced in this process are precipitated from the resolution filtrate and the filtrate may be discarded as effluent water without any danger to the environment.