17863-75-1Relevant academic research and scientific papers
Palladium-Catalyzed Decarboxylative γ-Arylation for the Synthesis of Tetrasubstituted Chiral Allenes
Scheipers, Ina,Mück-Lichtenfeld, Christian,Studer, Armido
, p. 6545 - 6548 (2019/04/17)
An enantiospecific palladium-catalyzed decarboxylative coupling of acyclic β,γ-alkynoic acids with various aryl iodides to chiral tetrasubstituted allenes is described. The coupling reaction comprises a decarboxylative γ-palladation of α,α-disubstituted carboxylic acids to provide the tetrasubstituted allenes with complete point-to-axial chirality transfer in excellent yields.
Copper catalyzed decarboxylative alkynylation of quaternary α-cyano acetate salts
Feng, Yi-Si,Xu, Zhong-Qiu,Mao, Long,Zhang, Feng-Feng,Xu, Hua-Jian
, p. 1472 - 1475 (2013/06/27)
Cu-catalyzed decarboxylative alkynylation of quaternary α-cyano acetate salts with alkynyl bromides and alkynyl chlorides is described. This new reaction can be used for preparing functionalized butynenitrile derivatives.
