17874-32-7

Basic information

• Product Name: 6-TERT-BUTYL-4-METHYLCOUMARIN
• Synonyms: 6-t-Butyl-4-methylcoumarin;6-tert-Butyl-4-methyl-2H-chromen-2-one;6-TERT-BUTYL-4-METHYLCOUMARIN;TIMTEC-BB SBB008027;Nsc20774;6-tert-Butyl-4-methylcoumarin ,98%;6-tert-butyl-4-methylchromen-2-one
• CAS NO: 17874-32-7
• Molecular Formula: C14H16O2
• Molecular Weight: 216.28
• Mol File: 17874-32-7.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 336.1ºC at 760 mmHg
• Flash Point: 139.3ºC
• Appearance: /
• Density: 1.071g/cm3
• Vapor Pressure: 0.000115mmHg at 25°C
• Refractive Index: 1.535
• CAS DataBase Reference: 6-TERT-BUTYL-4-METHYLCOUMARIN(CAS DataBase Reference)
• NIST Chemistry Reference: 6-TERT-BUTYL-4-METHYLCOUMARIN(17874-32-7)
• EPA Substance Registry System: 6-TERT-BUTYL-4-METHYLCOUMARIN(17874-32-7)

Safety Data

• Statements: 20/21/22
• Safety Statements: 24/25-36/37
• Hazardous Substances Data: 17874-32-7(Hazardous Substances Data)

Usage

Chemical Properties

White solid

InChI:InChI=1/C14H16O2/c1-9-7-13(15)16-12-6-5-10(8-11(9)12)14(2,3)4/h5-8H,1-4H3

Upstream product

• 3056-64-2 4-(tert-butyl)phenyl acetate 
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• 96-76-4 2,4-di-tert-Butylphenol 
• 1011493-09-6 2,4-di-tert-butylphenyl 3-oxobutanoate 
• 4116-18-1 ethyl 2-tert-butyl-3-oxobutanoate 
• 186407-60-3 4-tert-butylphenyl 3-oxobutanoate 
• 590-93-2 2-Butynoic acid 
• 57373-81-6 2-hydroxy-5-t-butyl-acetophenone 
• 108-24-7 acetic anhydride 

Relevant articles and documents

A new gold-catalyzed domino cyclization and oxidative coupling reaction

Gold-catalyzed domino cyclization and oxidative coupling reaction for synthesis of dicoumarins was studied. Gold was thought to be an unreactive metal before its catalyzed reaction was discovered. HAuCl4 was suspended in dry 1,2-dichloroethane (DCE), whereas protic solvent gave only monomer and UV absorption and fluorescence properties of dicoumarins were similar to those of monomers. The crude product was purified by flash column chromatography on silica and gold catalyst performed two different functions. Dicoumarins, scaffolds of natural products has interesting biological properties whereas, potential photostable UV-absorbent materials were accessed in two steps from commercially available starting materials. The reaction generally proceeded in moderate-to-good yields, tolerating a variety of substituents on the aromatic moiety.

New Method for Preparation of Coumarins and Quinolinones via Pd-Catalyzed Intramolecular Hydroarylation of C-C Triple Bonds

A new and general method has been developed for preparation of coumarins and quinolinones by intramolecular hydroarylation of alkynes. Various aryl alkynoates and alkynanilides undergo fast intramolecular reaction at room temperature in the presence of a