3056-64-2

Usage

Uses

Used in Fragrance Industry:
ACETIC ACID 4-TERT-BUTYLPHENYL ESTER is used as a fragrance ingredient for its ability to add a fruity note to various scents, particularly in perfumes and personal care products.
Used in Food Industry:
In the food industry, ACETIC ACID 4-TERT-BUTYLPHENYL ESTER is utilized as a flavoring agent to enhance the taste and aroma of various food products.
Safety Precautions:
It is important to handle ACETIC ACID 4-TERT-BUTYLPHENYL ESTER with caution due to its potential to cause skin and eye irritation. It should be stored in a cool, dry, and well-ventilated area to ensure its stability and safety.

Upstream product

• 98-54-4 para-tert-butylphenol 
• 108-24-7 acetic anhydride 
• 13031-43-1 4-acetyloxyacetophenone 
• 75-24-1 trimethylaluminum 
• 943-27-1 4'-t-butylacetophenone 
• 75-97-8 3,3-dimethyl-butan-2-one 
• 253185-03-4 tert-butylbenzene 
• 33035-41-5 2-(diacetoxyiodo)mesitylene 
• 3240-34-4 [bis(acetoxy)iodo]benzene 
• 18412-68-5 (4-tert-butylphenyl)trimethylsilane 
• 64-19-7 acetic acid 
• 108-05-4 vinyl acetate 
• 96-76-4 2,4-di-tert-Butylphenol 
• 75-07-0 acetaldehyde 

Downstream Products

• 57373-81-6 2-hydroxy-5-t-butyl-acetophenone 
• 98-54-4 para-tert-butylphenol 
• 17874-32-7 4-methyl-6-tert-butylcoumarin 
• 100245-06-5 1-(5-tert-butyl-2-hydroxy-3-nitrophenyl)ethanone 
• 288399-61-1 6-tert-butyl-4-oxo-4H-chromene-3-carbaldehyde 

Relevant academic research and scientific papers

Real time observation of the Photo-fries rearrangement

Two-color femtosecond pump probe spectroscopy was used to investigate the photo-Fries rearrangement of 4-tert-butylphenyl acetate (BPA) dissolved in cyclohexane. Broadband measurements were performed in the spectral range between 450 and 700 nm to confirm the wavelength dependence of the various signal contributions. The recombination of the radicals was found to occur within 13 ps. The time resolved absorption measurements on BPA provide strong evidence that after photoexcitation the S1 state is depopulated with a rate of 0.5 ps-1 by a mechanism which leads to the cleavage of the O-C bond and the generation of a radical pair.

An efficient method to prepare aryl acetates by the carbonylation of aryl methyl ethers or phenols

Synthesis of valuable chemicals from lignin based compounds is critical for the application of biomass. Here, we develop a method of preparing aryl acetates by the carbonylation of aryl methyl ethers or phenols under low CO pressure. Good to excellent yields of aryl acetates were obtained using different substrates, and a possible reaction mechanism was proposed by conducting a series of control experiments. This method may provide a potential way for the utilization of lignin.

Photo-Fries rearrangement in flow under aqueous micellar conditions

A flow edition of photo-Fries rearrangement for the synthesis of 2-acylphenols in an aqueous micellar medium has been described. We take advantage of a narrow channel reactor and micelle-induced confinement effect to refine both the efficiency and selectivity of the parent photoreaction. This journal is

Photoinduced Specific Acylation of Phenolic Hydroxy Groups with Aldehydes

A convenient method is reported to specifically acylate phenolic hydroxyl groups through a radical pathway. When a mixture of an aldehyde and a phenol in ethyl acetate is irradiated with blue light in the presence of iridium and nickel bromide catalysts at ambient temperature, phenoxyl and acyl radicals are transiently generated in situ and cross-couple to furnish an ester. Aliphatic hydroxy groups remain untouched under the reaction conditions.

Synthesis of Ti-Al binary oxides and their catalytic application for C-H halogenation of phenols, aldehydes and ketones

Traditional C–H halogenation of organic compounds often requires corrosive agent or harsh condition, and current researches are focused on the use of noble metals as catalyst. In order to give an efficient, benign, activity-adjustable and cost-effective system for halogenation, a series of Ti-Al mixed oxides are prepared as catalyst through sol-gel in this work. Characterizations reveal all catalysts contain more aluminum than titanium, but preparative conditions affect their composition and crystallinity. Monitoring of particle size, zeta potential and UV–vis of preparative solution reveals that formation of catalyst colloids undergoes chemical reaction, affecting catalyst morphology. In halogenation, all catalysts show moderate to high activities, copper chloride proves to be an effective halogen source rather than sodium chloride. The chlorination and bromination are better than iodization, phenol and ketone appear to be more appropriate substrates than aldehyde. Additionally, oxide backbone of catalyst is more durable than its organic components during recycling. This study may provide new catalytic materials for progress of C–H activation.

Continuous Production of Biorenewable, Polymer-Grade Lactone Monomers through Sn-Β-Catalyzed Baeyer–Villiger Oxidation with H2O2

The Baeyer–Villiger oxidation is a key transformation for sustainable chemical synthesis, especially when H2O2 and solid materials are employed as oxidant and catalyst, respectively. 4-substituted cycloketones, which are readily available from renewables, present excellent platforms for Baeyer–Villiger upgrading. Such substrates exhibit substantially higher levels of activity and produce lactones at higher levels of lactone selectivity at all values of substrate conversion, relative to non-substituted cyclohexanone. For 4-isopropyl cyclohexanone, which is readily available from β-pinene, continuous upgrading was evaluated in a plug-flow reactor. Excellent selectivity (85 % at 65 % conversion), stability, and productivity were observed over 56 h, with over 1000 turnovers (mol product per mol Sn) being achieved with no loss of activity. A maximum space–time yield that was almost twice that for non-substituted cyclohexanone was also obtained for this substrate [1173 vs. 607 g(product) kg(catalyst)?1 cm?3 h?1]. The lactone produced is also shown to be of suitable quality for ring opening polymerization. In addition to demonstrating the viability of the Sn-β/H2O2 system to produce renewable lactone monomers suitable for polymer applications, the substituted alkyl cyclohexanones studied also help to elucidate steric, electronic, and thermodynamic elements of this transformation in greater detail than previously achieved.

Synthesis method of 2-hydroxyl-3-nitroacetophenone

The invention provides a synthesis method of 2-hydroxyl-3-nitroacetophenone. Starting from p-tert-butylphenol, the synthesis method is used for synthesizing the 2-hydroxyl-3-nitroacetophenone through four-step reaction including the steps of esterification, Fries rearrangement, nitrification and disproportionation in sequence. Compared with the prior art, the synthesis method has the advantages that raw materials are easy to obtain and the cost is low; a product obtained by disproportionation reaction mainly comprises the p-tert-butylphenol and can be recycled, so that a few of wastes are generated and the synthesis method is clean and environment-friendly; after the reaction is finished, the product can be recycled after being simply filtered, so that the cost is reduced and the emission of the wastes is reduced; and the target product can be obtained in a high yield, and the total yield reaches 70% to 80%.

Size-selective catalysts in five functionalized porous coordination polymers with unsaturated zinc centers

The five reported structural isomorphic porous coordination polymers (PCPs) 1-5, namely, [Zn(L)(ip) (1), Zn(L)(aip) (2), Zn(L)(hip) (3), Zn(L)(nip) (4), and Zn(L)(HBTC) (5) (L = N4,N4′-di(pyridine-4-yl)biphenyl-4,4′-dicarboxamide, H2ip = isophthalic acid, H2aip = 5-aminoisophthalic acid, H2hip = 5-hydroxyisophthalic acid, H2nip = 5-nitroisophthalic acid, H3BTC = 1,3,5-benzenetricarboxylic acid)] were used to catalyze the acetylation of phenol. All these heterogeneous catalysts exhibit good catalytic efficiency and size-selectivity toward the acetylation of phenols owing to their unsaturated metal centers, non-coordinated amide, and suitable channel size and shape. Among them, 2 displays the highest catalytic activity and excellent cooperative catalysis due to the presence of basic non-coordinated amide groups.

Highly efficient and recyclable acetylation of phenols and alcohols by nickel zirconium phosphate under solvent-free conditions

Nickel zirconium phosphate nanoparticles have been used as an efficient catalyst for the acetylation of a wide range of alcohols and phenols with acetic anhydride in good to excellent yields under solvent-free conditions. The steric and electronic properties of the different substrates had a significant influence on the reaction conditions required to achieve the acetylation. The catalyst used in the current study was characterized by inductively coupled plasma optical emission spectroscopy, X-ray diffraction, N2 adsorption-desorption, scanning electron microscopy, and transmission electron microscopy. This nanocatalyst could also be recovered and reused at least six times without any discernible decrease in its catalytic activity.

A highly selective receptor for zwitterionic proline

A chiral chromane receptor has been synthesized which mimics the oxyanion hole of the enzymes. In this receptor H-bonds and cation-π interactions team up to generate an apolar host-guest complex with zwitterionic proline. This complex allows the extraction of only proline to a chloroform phase, while no other natural amino acids are extracted. Due to the chiral nature of the receptor, enantioselective extraction from the aqueous proline solution to a chloroform phase takes place. l-Proline provided an easy method to resolve the receptor racemic mixture, while anisotropic effects, NOE and CD studies revealed the absolute configuration of the receptor. Modelling studies also support the proposed structures. The presence of an oxyanion-hole motif in this structure was corroborated by X-ray diffraction studies.