Cas 178751-21-8,1-{6-[[(1<i>H</i>-benzoimidazol-2-yl)-hydrazono]-(4-nitro-phenyl)-methyl]-benzo[1,3]dioxol-5-yl}-propan-2-ol

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Check Digit Verification of cas no

The CAS Registry Mumber 178751-21-8 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,8,7,5 and 1 respectively; the second part has 2 digits, 2 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 178751-21:
(8*1)+(7*7)+(6*8)+(5*7)+(4*5)+(3*1)+(2*2)+(1*1)=168
168 % 10 = 8
So 178751-21-8 is a valid CAS Registry Number.

178751-21-8Upstream product

178751-21-8Downstream Products

178751-20-7 (R)-7-(2-benzimidazolyl)-8,9-dihydro-8-methyl-5-(4-nitrophenyl)-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepine

178751-21-8Relevant academic research and scientific papers

Synthesis and anticonvulsant activity of 3-aryl-5H-2,3-benzodiazepine AMPA antagonists

Anderson, Benjamin A.,Harn, Nancy K.,Hansen, Marvin M.,Harkness, Allen R.,Lodge, David,Leander, J. David

, p. 1953 - 1956 (2007/10/03)

A novel series of 3-aryl-5H-2,3-benzodiazepines with N-3 aromatic substituents has been synthesized. Good in vivo anticonvulsant activity of the new compounds has been demonstrated employing the maximal electroshock seizure test in mice. Evaluation of a subset of the compounds in the cortical wedge assay confirmed the new structures to be AMPA antagonists.

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