17879-45-7

Basic information

• Product Name: BIS-TRIMETHYLSILYLACETAMIDE
• Synonyms: BIS-TRIMETHYLSILYLACETAMIDE;LABOTEST-BB LT01406979;2,2-Bis(trimethylsilyl)acetamide
• CAS NO: 17879-45-7
• Molecular Formula: C₈H₂₁NOSi₂
• Molecular Weight: 203.43
• Mol File: 17879-45-7.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 241.4±30.0 °C(Predicted)
• Appearance: /
• Density: 0.872±0.06 g/cm3(Predicted)
• PKA: 16.24±0.50(Predicted)
• CAS DataBase Reference: BIS-TRIMETHYLSILYLACETAMIDE(CAS DataBase Reference)
• NIST Chemistry Reference: BIS-TRIMETHYLSILYLACETAMIDE(17879-45-7)
• EPA Substance Registry System: BIS-TRIMETHYLSILYLACETAMIDE(17879-45-7)

Safety Data

• Hazardous Substances Data: 17879-45-7(Hazardous Substances Data)

Downstream Products

• 439113-85-6 4-[1-(4-fluorophenylamino)-2-(2-oxo-4-phenyloxazolidine-3-carbonyl)-5-phenyl-5-trimethylsilanyloxypentyl]benzonitrile 
• 439113-86-7 4-[1-(4-Fluorophenyl)-3-(3-hydroxy-3-phenylpropyl)-4-oxo-azetidin-2-yl]benzo-nitrile 
• 246262-03-3 (5-hydroxypyridin-2-yl)carbamic acid benzyl ester 
• 782425-77-8 N-benzyl-[3,3-bis(4-methoxyphenyl)-1-methylpropyl]amine 
• 7288-28-0 2,4-bis(trimethylsiloxy)-5-methylpyrimidine 
• 10457-14-4 O,O'-bis-(trimethylsilyl)uracil 
• 72536-17-5 C₉H₁₈O₂Si 
• 3965-63-7 tert-butylperoxytrimethylsilane 
• 14642-79-6 benzyloxy-trimethylsilane 
• 2078-16-2 trimethylsilyl 3,4-dimethoxybenzoate 
• 61040-75-3 ((3,4-dimethoxybenzyl)oxy)trimethylsilane 
• 2078-14-0 4-methoxybenzoic acid trimethylsilyl ester 
• 99794-93-1 C₂₀H₂₈O₅Si 
• 2078-18-4 trimethylsilyl 2-phenylacetate 

Relevant articles and documents

PNA synthesis using a base-labile amino protecting group

PNA synthesis using a base-labile amino protecting group Processes are described for preparing PNA oligomers, in which R0 is hydrogen, alkanoyl, alkoxycarbonyl, cycloalkanoyl, aroyl, heteroaroyl, or a group which favors the intracellular uptake of the oligomer, A and Q are amino acid residues, k and 1 are 0 to 20, n is 1-50, B is a nucleotide base which is customary in nucleotide chemistry, and Q0 is OH, NH2, or alkylamino which can be substituted by OH or NH2. In these processes, the amino acid residues and the structural components in which PG is a base-labile amino protecting group and B' is a nucleotide base which is protected on its exocyclic amino function, are coupled step-wise, in accordance with the solid-phase method, onto a polymeric support which is provided with an anchor group, and, after the construction is complete, the target compounds are cleaved from the polymeric support using a cleaving reagent. Intermediates of the PNA oligomers are also described, as are processes for their preparation.