2078-18-4

Basic information

• Product Name: PHENYLACETOXYTRIMETHYLSILANE
• Synonyms: Acetic acid, phenyl-, trimethylsilyl ester;Phenylacetic acid, monoTMS;Trimethylsilyl phenylacetate;PHENYLACETOXYTRIMETHYLSILANE
• CAS NO: 2078-18-4
• Molecular Formula: C₁₁H₁₆O₂Si
• Molecular Weight: 208.33
• Product Categories: C10 to C11;Carbonyl Compounds;Esters
• Mol File: 2078-18-4.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 96-97 °C0.7 mm Hg(lit.)
• Flash Point: 171 °F
• Appearance: /
• Density: 0.982 g/mL at 25 °C(lit.)
• Vapor Pressure: 0.0459mmHg at 25°C
• Refractive Index: n20/D 1.478(lit.)
• CAS DataBase Reference: PHENYLACETOXYTRIMETHYLSILANE(CAS DataBase Reference)
• NIST Chemistry Reference: PHENYLACETOXYTRIMETHYLSILANE(2078-18-4)
• EPA Substance Registry System: PHENYLACETOXYTRIMETHYLSILANE(2078-18-4)

Safety Data

• Safety Statements: 24/25
• RIDADR: NA 1993 / PGIII
• WGK Germany: 3
• TSCA: No
• Hazardous Substances Data: 2078-18-4(Hazardous Substances Data)

Usage

General Description

PHENYLACETOXYTRIMETHYLSILANE, also known as PAMTS, is an organosilicon compound that is commonly used as a crosslinking agent in the production of silicone rubber. It is a clear, colorless liquid with a pungent odor and is highly reactive. PAMTS is often used in the manufacturing of silicone products such as sealants, adhesives, and elastomers due to its ability to improve the mechanical and thermal properties of the materials. It is also used as a reagent in organic synthesis to introduce trimethylsilyl functional groups into organic molecules. Proper handling and storage of PAMTS are essential as it can react violently with water and is highly flammable.

InChI:InChI=1/C11H16O2Si/c1-14(2,3)13-11(12)9-10-7-5-4-6-8-10/h4-8H,9H2,1-3H3

Upstream product

• 103-82-2 phenylacetic acid 
• 72658-09-4 (E)-(1-methoxyprop-1-enyloxy)trimethylsilane 
• 25561-30-2 N,O-Bis(trimethylsilyl)trifluoroacetamide 
• 999-97-3 1,1,1,3,3,3-hexamethyl-disilazane 
• 60-12-8 2-phenylethanol 
• 17879-45-7 bis-(trimethylsilyl)acetamide 
• 75-77-4 chloro-trimethyl-silane 

Downstream Products

• 7500-45-0 N-benzylphenylacetamide 
• 29313-32-4 2-phenylacetyl isothiocyanate 
• 125294-36-2 3-hydroxyphenylmaleic anhydride 
• 31491-21-1 2-phenyl-1,1-bis(trimethylsilyloxy)ethene 
• 103-82-2 phenylacetic acid 
• 122-78-1 phenylacetaldehyde 
• 60-12-8 2-phenylethanol 
• 621-06-7 2,N-diphenylacetamide 
• 140-29-4 phenylacetonitrile 
• 1555-80-2 phenylacetic anhydride 
• 64277-60-7 Phenylketen-bis--acetal 

Relevant articles and documents

Synthesis of trimethylsilyl carboxylates by HMDS under solvent-free conditions

A broad set of structurally different carboxylic acids were transformed into their trimethylsilyl esters with HMDS in a practically completely solvent-free process, while a catalytic amount of iodine was required in some cases. The process has several advantages over the known methods: untreated reactants, air atmosphere, mild and neutral conditions, no evolution of hydrogen halide, no need of an additional base, low amount of waste, completely without chromatography, low consumption of energy, and operational simplicity.

Partition coefficients of ketones, phenols, aliphatic and aromatic acids, and esters in n-hexane/nitromethane

Liquid-liquid partition is used in sample preparation and in countercurrent and liquid-liquid chromatographic separations. Partition coefficients are widely used in toxicology, environmental, and analytical chemistry. The K hn determination procedure for the n-hexane/ nitromethane system was optimized and partition coefficients for 99 ketones, esters and trimethylsilyl derivatives of phenols, aliphatic and aromatic acids were determined. For 130 compounds, Khn values were predicted using mathematical relationships between Khn and other physicochemical and structural parameters. Versita Sp. z o.o.

Spectroscopic properties of the partial β-agonist doxaminol (BM 10.188) and its metabolites

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