17889-09-7Relevant academic research and scientific papers
Synthesis and antioxidant activities of novel 4-Schiff base-7-benzyloxy- coumarin derivatives
Zhang, Ye,Zou, Biqun,Chen, Zhenfeng,Pan, Yingming,Wang, Hengshan,Liang, Hong,Yi, Xianghui
, p. 6811 - 6815 (2011)
4-Schiff base-7-benzyloxy-coumarins 5a1-5h2 and its derivative 6 were designed and synthesized based on the 7-benzyloxy-coumarin structure as novel antioxidants. The in vitro antioxidant activities screening revealed that 2,2-diphenyl-1-picrylhydrazyl (DPPH) radical scavenging activities of compounds 5b1, 5d1, 5f1, 5f2, 5g1 and 5g2, and 2,2′-azinobis-(3- ethylbenzthiazoline-6-sulfonate) cation (ABTS+) radical scavenging activities of compounds 5a1, 5b1, 5c1, 5c 2, 5d1, 5e1, 5e2, 5f2, 5g1, 5g2 and 5h1 were better than that of the commercial antioxidant butylated hydroxytoluene (BHT), while the superoxide anion radical scavenging activities of 5a2 and 5g2 were stronger than that of the commercial antioxidant butylated hydroxyanisole (BHA), and the hydroxyl radical scavenging activity of 5e1 was much better than that of the common antioxidant ascorbic acid.
