178929-81-2Relevant academic research and scientific papers
Synthesis, ligand binding, and quantitative structure-activity relationship study of 3β-(4'-substituted phenyl)-2β-heterocyclic tropanes: Evidence for an electrostatic interaction at the 2β-position
Kotian, Pravin,Mascarella, S. Wayne,Abraham, Philip,Lewin, Anita H.,Boja, John W.,Kuhar, Michael J.,Carroll, F. Ivy
, p. 2753 - 2763 (2007/10/03)
A set of 3β-(4'-substituted phenyl)-2β-heterocyclic tropanes was designed, synthesized, and characterized. We discovered that these compounds can function as bioisosteric replacements for the corresponding WIN 35,065-2 analogs which possess a 2β-carbometh
