178944-70-2

Upstream product

• 178944-68-8 8-(1-Benzenesulfonyl-1H-indol-2-yl)-9-(2-benzyloxy-ethyl)-1,5-dithia-9-aza-spiro[5.5]undecane 
• 178944-67-7 7-(1-Benzenesulfonyl-1H-indol-2-yl)-8-(2-benzyloxy-ethyl)-1,4-dioxa-8-aza-spiro[4.5]decane 
• 178944-69-9 2-[8-(1-Benzenesulfonyl-1H-indol-2-yl)-1,5-dithia-9-aza-spiro[5.5]undec-9-yl]-ethanol 
• 54555-84-9 benzyl iodoethyl ether 
• 178944-65-5 2-(1-Benzenesulfonyl-1H-indol-2-yl)-1-(2-benzyloxy-ethyl)-piperidin-4-one 
• 100-39-0 benzyl bromide 
• 142207-40-7 2-<1-(phenylsulfonyl)-2-indolyl>-4-piperidone ethylene acetal 

Downstream Products

• 178944-93-9 C₃₅H₃₅N₃O₆S₂ 

Relevant academic research and scientific papers

Synthetic applications of 2-aryl-4-piperidones. XI a new synthesis of the E-azaeburnamine skeleton

17-Azaeburnamine type compound 2 is synthesized by closure of ring E on 1-aminoindolo[2,3-a]quinolizidine 8. Compound 8 is obtained by a Neber rearrangement on the corresponding indolo[2,3- a]quinolizidin-2-one, or by K(t)BuO cyclisation of 3-amino-2-(2- indolyl)piperidin-4-one 16. In both cases the starting substrate is 4-piperidone 3. The synthesis of the new [ABED] ring system 6 is also described.