178964-46-0

Upstream product

• 2622-05-1 allylmagnesium bromide 
• 178912-16-8 Acetic acid (2R,3R,4aS,9aR)-2-formyl-6,6,9a-trimethyl-octahydro-1,5-dioxa-benzocyclohepten-3-yl ester 
• 1730-25-2 allylmagnesium bromide 
• 57745-82-1 trans-1,1,5-trimethyloct-4-en-1,7-diol 
• 178912-07-7 (2S,3R)-2-Allyl-3,7,7-trimethyl-oxepan-3-ol 
• 178912-08-8 (E)-4-((2S,3R)-3,7,7-Trimethyl-3-trimethylsilanyloxy-oxepan-2-yl)-but-2-enoic acid methyl ester 
• 178912-10-2 (2S,3R)-3-((2S,3R)-3,7,7-Trimethyl-3-trimethylsilanyloxy-oxepan-2-ylmethyl)-oxirane-2-carbaldehyde 
• 178912-09-9 [(2R,3R)-3-((2S,3R)-3,7,7-Trimethyl-3-trimethylsilanyloxy-oxepan-2-ylmethyl)-oxiranyl]-methanol 

Relevant academic research and scientific papers

Stereoselective synthesis of ABC-ring system of hemibrevetoxin B

The 6, 6, 7-membered tricyclic ether ring system (ABC-ring) of hemibrevetoxin B was stereoselectively synthesized. The crucial steps in the present synthesis involve the ring expansion of tetrahydropyran to oxepane, 6-endo cyclization of epoxy alcohol, an