178985-68-7Relevant academic research and scientific papers
Palladium-catalyzed silyl C(sp3)-H bond activation
Liang, Yun,Geng, Weizhi,Wei, Junnian,Ouyang, Kunbing,Xi, Zhenfeng
supporting information; experimental part, p. 1537 - 1542 (2012/03/22)
The first transition-metal-catalyzed activation of silyl C(sp 3)-H bond was realized and synthetically applied. A variety of organic skeletons substituted with SiMe3 groups could undergo the Pd-catalyzed intramolecular coupling react
Palladium-catalyzed synthesis of benzosilolo[2,3- b ]indoles via cleavage of a C(sp3)-Si bond and consequent intramolecular C(sp 2)-Si coupling
Liang, Yun,Zhang, Shaoguang,Xi, Zhenfeng
supporting information; experimental part, p. 9204 - 9207 (2011/08/06)
An efficient process involving Pd-catalyzed selective cleavage of a C(sp3)-Si bond and consequent intramolecular C(sp2)-Si coupling has been developed, affording benzosilolo[2,3-b]indoles as a new type of silicon-bridged polyheteroarene in excellent yields. Aldehyde was found for the first time to be able to promote the efficiency of the catalytic process remarkably.
Synthesis of unsymmetrically substituted biaryls via sequential lithiation of dibromobiaryls using integrated microflow systems
Nagaki, Aiichiro,Takabayashi, Naofumi,Tomida, Yutaka,Yoshida, Jun-Ichi
supporting information; experimental part, (2010/04/22)
A microflow system consisting of micromixers and microtube reactors provides an effective method for the introduction of two electrophiles onto dibromobiaryls. Selective monolithiation of dibromobiaryls, such as 2,2'-dibromobiphenyl, 4,4'-dibromobiphenyl, 2,7-dibromo-9,9-dioctylfluorene, 2,2'-dibromo-1,1'-binaphthyl, and 2,2'-dibromobibenzyl with 1 equiv of n-butyllithium followed by the reaction with electrophiles was achieved using a microflow system by virtue of fast micromixing and precise temperature control. Sequential introduction of two different electrophiles was achieved using an integrated microflow system composed of four micromixers and four microtube reactors to obtain unsymmetrically substituted biaryl compounds.
Selective monolithiation of dibromobiaryls using microflow systems
Nagaki, Aiichiro,Takabayashi, Naofumi,Tomida, Yutaka,Yoshida, Jun-ichi
supporting information; experimental part, p. 3937 - 3940 (2009/06/18)
(Chemical Equation Presented) Selective monolithiation of dibromobiaryls, such as 2,2′-dibromobiphenyl, 4,4′-dibromobiphenyl, 2,7-dibromo-9,9-dioctylfluorene, 2,2′-dibromo-1,1′-binaphthyl, and 5,5′-dibromo-2,2′-bithiophene, with 1 equiv of n-butyllithium followed by the reaction with electrophiles was achieved using a microflow system by virtue of fast micromixing and precise temperature control. Sequential introduction of two different electrophiles based on this method was also achieved using a microflow system composed of four micromixers and four microtube reactors.
Lithium-2-2'-biphenyldiyltrimethylsilicat: erstmalige Beobachtung von Pentaorganosilicaten
Keijzer, Adrianus H. J. F. de,Kanter, Franciscus J. J. de,Schakel, Marius,Schmitz, Robert F.,Klumpp, Gerhard W.
, p. 1183 - 1184 (2007/10/03)
Keywords: Lithiumverbindungen; NMR-Spektroskopie; Siliciumverbindungen; Substitutionen
THE SYNTHESIS AND REACTIONS OF ortho BROMOPHENYLLITHIUM
Chen, Loomis S.,Chen, Grace J.,Tamborski, Christ
, p. 283 - 292 (2007/10/02)
Experimental conditions have now been developed whereby o-bromophenyl-lithium(II) may be prepared in excellent yields and used as an organometallic intermediate for the synthesis of a variety of ortho bromo substituted phenyl compounds (o-BrC6H4X).The thermal stability, decomposition products and reactions of II were studied.Reactions between II and a variety of substrates, e.g., CO2, dimethylformamide, fluorinated esters, hexafluorobenzene, and organosilicon chlorides were examined.
