178995-74-9

Upstream product

• 536-74-3 phenylacetylene 
• 166247-63-8 7-deaza-2'-deoxy-7-iodoadenosine 
• 123148-78-7 4-chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidine 
• 178995-71-6 9-(β-D-2'-deoxyribofuranosyl)-6-chloro-7-iodo-7-deazapurine 
• 4330-21-6 2-deoxy-3,5-di-O-p-toluoyl-α-D-erythro-pentofuranosyl chloride 

Downstream Products

• 259097-05-7 7-(2-deoxy-β-D-erythro-pentofuranosyl)-N⁴-[(dimethylamino)methylidene]-5-(phenylethynyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 
• 259096-95-2 7-[2-deoxy-5-O-(4,4'-dimethoxytriphenylmethyl)-β-D-erythro-pentofuranosyl]-N⁴-[(dimethylamino)methylidene]-5-(phenylethynyl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine 3'-(2-cyanoethyl diisopropylphosphoramidite) 

Relevant academic research and scientific papers

Palladium-catalyzed cross coupling of 7-iodo-2'-deoxytubercidin with terminal alkynes

The 7-alkynyl-2'-deoxytubercidins (7-deaza-2'-deoxyadenosines) 7-17 have been prepared by the Pd(0)/Cu(I)-catalyzed cross coupling of 7-iodo-2'-deoxytubercidin (2d) with terminal alkynes. The coupling products include 17α-ethynyltestosterone and 17α-ethynylestradiol derivatives (16, 17).