179020-07-6Relevant articles and documents
Synthesis of potent leukotriene A4 hydrolase inhibitors. Identification of 3-[methyl[3-[4-(phenylmethyl)phenoxy]propyl]amino]propanoic acid
Penning, Thomas D.,Russell, Mark A.,Chen, Barbara B.,Chen, Helen Y.,Liang, Chi-Dean,Mahoney, Matthew W.,Malecha, James W.,Miyashiro, Julie M.,Yu, Stella S.,Askonas, Leslie J.,Gierse, James K.,Harding, Elizabeth I.,Highkin, Maureen K.,Kachur, James F.,Kim, Suzanne H.,Villani-Price, Doreen,Pyla, E. Yvonne,Ghoreishi-Haack, Nayereh S.,Smith, Walter G.
, p. 3482 - 3490 (2002)
Leukotriene B4 (LTB4) is a potent, proinflammatory mediator involved in the pathogenesis of a number of diseases including inflammatory bowel disease, psoriasis, rheumatoid arthritis, and asthma. The enzyme LTA4 hydrolase
