179033-27-3Relevant academic research and scientific papers
Thalidomide analogs and PDE4 inhibition
Muller, George W.,Shire, Mary G.,Wong, Lu Min,Corral, Laura G.,Patterson, Rebecca T.,Chen, Yuxi,Stirling, David I.
, p. 2669 - 2674 (1998)
N-Phthaloyl 3-amino-3-arylpropionic acid analogs of thalidomide that are potent inhibitors of tumor necrosis factor-α are reported. These compounds were found to be potent inhibitors of phosphodiesterase 4.
