179057-11-5

Basic information

• Product Name: 4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester
• Synonyms: 4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester;Methyl 4-(1-methyl-1H-pyrazol-3-yl)benzoate;methyl 4-(1-methylpyrazol-3-yl)benzoate
• CAS NO: 179057-11-5
• Molecular Formula: C₁₂H₁₂N₂O₂
• Molecular Weight: 216.23588
• Mol File: 179057-11-5.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 357.507 °C at 760 mmHg
• Flash Point: 170.015 °C
• Appearance: /
• Density: 1.16
• CAS DataBase Reference: 4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester(179057-11-5)
• EPA Substance Registry System: 4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester(179057-11-5)

Safety Data

• Hazardous Substances Data: 179057-11-5(Hazardous Substances Data)

Usage

General Description

4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester, also known as 1-Methyl-3-(4-methylcarbamoylphenyl)pyrazole-5-carboxylic acid methyl ester, is a chemical compound with the molecular formula C16H16N2O3. It is a methyl ester of 4-(1-methyl-1H-pyrazol-3-yl)benzoic acid and is commonly used in research and chemical synthesis. 4-(1-Methyl-1H-pyrazol-3-yl)benzoic acid methyl ester is a derivative of pyrazole and benzoic acid, and it may have various applications in pharmaceuticals, agrochemicals, and other industrial processes. It is important to handle this compound with care and follow safety regulations when working with it in laboratory settings.

Upstream product

• 60-34-4 methylhydrazine 
• 114431-72-0 (E)-methyl 4-(3-(dimethylamino)acryloyl)benzoate 
• 151049-87-5 3-bromo-1-methyl-1H-pyrazole 
• 99768-12-4 4-methoxycarbonylphenylboronic acid 
• 701215-21-6 methyl 4-[3-(dimethylamino)-1-oxo-2-propen-1-yl]benzoate 
• 208511-67-5 4-(2H-pyrazol-3-yl)-benzoic acid 
• 74-88-4 methyl iodide 
• 38430-55-6 ethyl-4-acetylbenzoate 

Downstream Products

• 915707-39-0 4-(1-methyl-1H-pyrazol-3-yl)benzoic acid 
• 179056-67-8 Benzyl-[4-(1-methyl-1H-pyrazol-3-yl)-benzyl]-amine 
• 179055-66-4 Cycloheptyl-[4-(1-methyl-1H-pyrazol-3-yl)-benzyl]-amine 
• 179055-27-7 4-(1-methyl-1H-pyrazol-3-yl)benzaldehyde 
• 179055-20-0 (4-(1-methyl-1H-pyrazol-3-yl)phenyl)methanol 

Relevant articles and documents

NITROGEN-CONTAINING FUSED BICYCLIC COMPOUNDS AND THEIR USE AS UBIQUITIN-SPECIFIC-PROCESSING PROTEASE 1 (USP1) INHIBITORS

The present disclosure provides compounds having Formula (I): (I) and the pharmaceutically acceptable salts and solvates thereof, wherein X1, X2, X3, X4, X5, X6, X7, X8, R1, R2, R6, R6', R7, and R7' are defined as set forth in the specification. The present disclosure is also directed to the use of compounds of Formula (I) to inhibit a USP1 protein and/or to treat a disorder responsive to the inhibition of USP1 proteins and USP1 activity. Compounds of the present disclosure are especially useful for treating cancer.

PIPERAZINE AND PIPERIDINE BIARYL DERIVATIVES

This invention relates to piperazine and piperidine biaryl compounds of Formula (I) or a pharmaceutically acceptable prodrug, salt, polymorph, solvate, enantiomer, diastereomer, racemate, mixture of stereoisomers thereof, or derivative thereof; and to processes for preparing the compounds or pharmaceutical compositions containing the same. The compounds and pharmaceutical compositions of the present invention are provided for use in the treatment of HIV infection and/or AIDS.