179073-10-0 Usage
Uses
Used in Pharmaceutical Industry:
1-[(2R,6S)-6-(hydroxyMethyl)-2-Morpholinyl]-5-Methyl-2,4(1H,3H)-PyriMidinedione is used as a reactant in the synthesis of protected morpholino monomers and morpholinoglycine oligonucleotide. These protected monomers and oligonucleotides are essential building blocks for the development of novel therapeutic agents, particularly in the field of antisense and RNA interference technologies. They can be used to modulate gene expression and target specific RNA sequences, offering potential treatments for various genetic disorders and diseases.
Used in Chemical Synthesis:
1-[(2R,6S)-6-(hydroxyMethyl)-2-Morpholinyl]-5-Methyl-2,4(1H,3H)-PyriMidinedione is also used as a versatile intermediate in the synthesis of various organic compounds. Its unique structure allows for further functionalization and modification, making it a valuable component in the development of new pharmaceuticals, agrochemicals, and other specialty chemicals. Its reactivity and stability make it suitable for use in a wide range of chemical reactions, including condensation, substitution, and rearrangement processes.
Check Digit Verification of cas no
The CAS Registry Mumber 179073-10-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,0,7 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 179073-10:
(8*1)+(7*7)+(6*9)+(5*0)+(4*7)+(3*3)+(2*1)+(1*0)=150
150 % 10 = 0
So 179073-10-0 is a valid CAS Registry Number.
179073-10-0Relevant academic research and scientific papers
Solid-phase-supported synthesis of morpholinoglycine oligonucleotide mimics
Abramova, Tatyana V.,Belov, Sergey S.,Tarasenko, Yulia V.,Silnikov, Vladimir N.
supporting information, p. 1151 - 1158 (2014/06/09)
An efficient solid-phase-supported peptide synthesis (SPPS) of morpholinoglycine oligonucleotide (MorGly) mimics has been developed. The proposed strategy includes a novel specially designed labile linker group containing the oxalyl residue and the 2-aminomethylmorpholino nucleoside analogues as first subunits.
