179174-82-4

Basic information

• Product Name: (Z)-4-acetoxy-3-(4-(methylsulfonyl)phenyl)-2-(3,4-difluorophenyl)-2-butenal
• Synonyms: (Z)-4-acetoxy-3-(4-(methylsulfonyl)phenyl)-2-(3,4-difluorophenyl)-2-butenal
• CAS NO: 179174-82-4
• Molecular Weight: 394.396
• Mol File: 179174-82-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: (Z)-4-acetoxy-3-(4-(methylsulfonyl)phenyl)-2-(3,4-difluorophenyl)-2-butenal(CAS DataBase Reference)
• NIST Chemistry Reference: (Z)-4-acetoxy-3-(4-(methylsulfonyl)phenyl)-2-(3,4-difluorophenyl)-2-butenal(179174-82-4)
• EPA Substance Registry System: (Z)-4-acetoxy-3-(4-(methylsulfonyl)phenyl)-2-(3,4-difluorophenyl)-2-butenal(179174-82-4)

Safety Data

• Hazardous Substances Data: 179174-82-4(Hazardous Substances Data)

Upstream product

• 658-93-5 (3,4-difluorophenyl)acetic acid 
• 50413-24-6 2-bromo-1-(4-methanesulfonylphenyl)ethanone 
• 162011-83-8 3-(3,4-difluorophenyl)-4-[4-(methylsulfonyl)phenyl]furan-2(5H)-one 
• 179174-80-2 (2Z)-2-(3,4-difluorophenyl)-3-[4-(methylsulfonyl)phenyl]but-2-ene-1,4-diol 
• 179174-81-3 (2Z)-3-(3,4-difluorophenyl)-4-hydroxy-2-[4-(methylsulfonyl)phenyl]but-2-en-1-yl acetate 

Downstream Products

• 179174-83-5 (2Z)-4-(acetoxy)-2-(3,4-difluorophenyl)-3-[4-(methylsulfonyl)phenyl]but-2-enoic acid 

Relevant articles and documents

WATER SOLUBLE PRODRUGS OF COX-2 INHIBITORS

Disclosed are water soluble compounds which are useful as prodrugs of COX-2 inhibitors, and pharmaceutical compositions comprising them.

Stilbene derivatives useful as cyclooxygenase-2 inhibitors

The invention encompasses novel compounds of Formula Iuseful in the treatment of cyclooxygenase-2 mediated diseases. STR1 The invention also encompasses certain pharmaceuticalcompositions and methods for treatment of cyclooxygenase-2 mediated diseases comprising the use of compounds of Formula I.