17936-74-2

Basic information

• Product Name: BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)-
• Synonyms: BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)-;2,2,2-Trichloro-1-o-tolylethanol
• CAS NO: 17936-74-2
• Molecular Formula: C₉H₉Cl₃O
• Molecular Weight: 239.52616
• Mol File: 17936-74-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 310°C at 760 mmHg
• Flash Point: 141.3°C
• Appearance: /
• Density: 1.4g/cm³
• Vapor Pressure: 0.000265mmHg at 25°C
• Refractive Index: 1.577
• CAS DataBase Reference: BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)-(17936-74-2)
• EPA Substance Registry System: BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)-(17936-74-2)

Safety Data

• Hazardous Substances Data: 17936-74-2(Hazardous Substances Data)

Usage

General Description

BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)- is a chemical compound that contains a benzene ring and a trichloromethyl group. Also known as benzyl alcohol, this compound is commonly used as a solvent in various industrial processes and as a preservative in pharmaceuticals. The trichloromethyl group adds an element of reactivity and can be used in organic synthesis to introduce this functional group into other molecules. BenzeneMethanol, 2-Methyl-.alpha.-(trichloroMethyl)- has properties that make it useful in a range of applications, from cleaning and degreasing to pharmaceutical manufacturing. However, it should be handled with care due to its potential health and environmental hazards.

InChI:InChI=1/C9H9Cl3O/c1-6-4-2-3-5-7(6)8(13)9(10,11)12/h2-5,8,13H,1H3

Upstream product

• 932-31-0 ortho-tolylmagnesium bromide 
• 75-87-6 chloral 
• 67-66-3 chloroform 
• 529-20-4 2-methylphenyl aldehyde 

Downstream Products

• 1620143-42-1 ethyl 2,2,2-trichloro-1-o-tolylethyl carbonate 
• 65085-89-4 1-(2,2-dichlorovinyl)-2-methylbenzene 
• 339274-28-1 (R)-2,2,2-trichloro-1-(2-methylphenyl)ethanol 
• 124787-10-6 2,2,2-trichloro-1-(2-methylphenyl)ethanone 

Relevant articles and documents

A novel β-(oxy)alkyl radical during copper(I)-mediated stereoselective synthesis of (Z)-ene-1,4-diones in a reaction of 2,2,2-trichloro-1-phenylethanone

A novel β-(oxy)alkyl radical derived from trichloro methyl compound containing neither a suitably located C-C multiple bond nor a leaving group or a H-atom at the β-position of the radical in a reaction of 2,2,2-trichloro-1-phenyl-ethanone with 2 mol equiv each of CuCl and bpy in refluxing DCE under a N2 atm underwent intramolecular heterolysis (just like formation of intact radical cation-anion pair) during stereoselective radical dimerization to Z-ene-1,4-dione along with small amount of reductive dechlorination product. The stereochemistry was established by X-ray diffraction spectroscopy of various solid crystalline products.

A practical asymmetric synthesis of homochiral α-arylglycines

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral α-arylglycines in high e.e.