179458-13-0Relevant academic research and scientific papers
Imidazole and triazole substituted ether phospholipids: Potent antitumor agents
Nair, Haridasan K.,Peterson, Andrew C.,Yazdi, Parvin T.,Franzmair, Rudolf
, p. 2379 - 2382 (2007/10/03)
Two novel ether phospholipids containing an imidazole and a triazole at the C-2 position of the glyceryl chain, respectively, were synthesized and evaluated as antitumor agents. Both compounds inhibited the growth of a number of tumor cell lines in vitro; IC50 values ranged from 1 to 6 μM for MCF-7, MDA-MB-231, HT-29 and HL-60 tumor cell lines.
