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17946-87-1

17946-87-1

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17946-87-1 Usage

Uses

Leucomisine is an antiinflammatory and angioprotective sesquiterpene.

Check Digit Verification of cas no

The CAS Registry Mumber 17946-87-1 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,7,9,4 and 6 respectively; the second part has 2 digits, 8 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 17946-87:
(7*1)+(6*7)+(5*9)+(4*4)+(3*6)+(2*8)+(1*7)=151
151 % 10 = 1
So 17946-87-1 is a valid CAS Registry Number.
InChI:InChI=1/C15H18O3/c1-7-4-5-10-9(3)15(17)18-14(10)13-8(2)6-11(16)12(7)13/h6,9-10,13-14H,4-5H2,1-3H3/t9-,10-,13-,14-/m0/s1

17946-87-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name (3S,3aS,9aS,9bS)-3,6,9-Trimethyl-3,3a,4,5,9a,9b-hexahydroazuleno[ 4,5-b]furan-2,7-dione

1.2 Other means of identification

Product number -
Other names ACHILLIN

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:17946-87-1 SDS

17946-87-1Relevant articles and documents

White,Marx

, p. 5511 (1967)

Structure-Activity Relationship in the Gastric Cytoprotective Effect of Several Sesquiterpene Lactones

Giordano, Oscar S.,Pestchanker, Mauricio J.,Guerreiro, Eduardo,Saad, Jose R.,Enriz, Ricardo D.,et al.

, p. 2452 - 2458 (2007/10/02)

The structural requirements for the gastric cytoprotective activity of several seaquiterpene lactones are reported.A theoretical-experimental study on the potentially active centers is carried out.The biological evaluation of reduced analogues and the simulation of the molecular interactions between these compounds and an endogenous cysteine residue suggest that the presence of a non sterically hindered Michael acceptor seems to be an essential structural requirement for the cytoprotective activity in this family of compounds.This observation suggests that cytoprotection is mediated through a Michael reaction between the sulfhydryl-containing peptides of the mucosa and Michael acceptors present in the molecules under study.This mechanism of action is in addition to and distinct from the one proposed in our previous paper, namely, that these sesquiterpenes stimulate endogenous synthesis of prostaglandins.

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