Dehydroleucodine is a natural sesquiterpene lactone compound derived from various plants, particularly those in the Asteraceae family. It is recognized for its potential pharmaceutical applications, including the treatment of cancer and inflammation. Characterized by its ability to induce cell death in cancer cells, inhibit cell proliferation, and promote DNA damage, dehydroleucodine also exhibits anti-inflammatory properties by suppressing the production of pro-inflammatory mediators. Furthermore, it demonstrates antioxidant and hepatoprotective effects, positioning it as a promising bioactive compound for therapeutic applications in traditional medicine.
36150-07-9
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Basic information
- Product Name: dehydroleucodine
- Synonyms: dehydroleucodine;(3aS)-3-Methylene-6,9-dimethyl-3,3aβ,4,5,9aβ,9bα-hexahydroazuleno[4,5-b]furan-2,7-dione;(3aS)-6,9-Dimethyl-3-methylene-3,3a,4,5,9aβ,9bα-hexahydroazuleno[4,5-b]furan-2,7-dione;3-Methylene-6,9-dimethyl-3,3aβ,4,5,9aβ,9bα-hexahydroazuleno[4,5-b]furan-2,7-dione;Dehydroleucodin;Lidbeckialactone;[3aS-(3aalpha,9aalpha,9bbeta)]-3,3a,4,5,9a,9b-hexahydro-6,9-dimethyl-3-methylene-azuleno[4,5-b]furan-2,7-dione;11,13-Dehydroleucodin
- CAS NO:36150-07-9
- Molecular Formula: C15H16O3
- Molecular Weight: 244.28574
- EINECS: N/A
- Product Categories: N/A
- Mol File: 36150-07-9.mol
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Chemical Properties
- Melting Point: N/A
- Boiling Point: 450.6°Cat760mmHg
- Flash Point: 203.1°C
- Appearance: white to off-white/
- Density: 1.2g/cm3
- Vapor Pressure: 2.61E-08mmHg at 25°C
- Refractive Index: 1.562
- Storage Temp.: room temp
- Solubility: DMSO: ≥30mg/mL
- CAS DataBase Reference: dehydroleucodine(CAS DataBase Reference)
- NIST Chemistry Reference: dehydroleucodine(36150-07-9)
- EPA Substance Registry System: dehydroleucodine(36150-07-9)
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Safety Data
- Hazard Codes: N/A
- Statements: N/A
- Safety Statements: N/A
- WGK Germany: 3
- RTECS:
- HazardClass: N/A
- PackingGroup: N/A
- Hazardous Substances Data: 36150-07-9(Hazardous Substances Data)
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36150-07-9 Usage
Uses
Used in Pharmaceutical Applications:Dehydroleucodine is used as an anticancer agent for its ability to induce apoptosis in cancer cells, inhibit their proliferation, and cause DNA damage, thereby offering a potential therapeutic intervention for cancer treatment.
Used in Anti-Inflammatory Applications:
Dehydroleucodine is utilized as an anti-inflammatory agent due to its capacity to inhibit the production of pro-inflammatory mediators such as nitric oxide and cytokines, making it a candidate for treating inflammatory conditions.
Used in Antioxidant and Hepatoprotective Applications:
Dehydroleucodine serves as an antioxidant, protecting cells from oxidative stress, and exhibits hepatoprotective effects, which may be beneficial in liver-related health issues.
Used in Traditional Medicine:
Dehydroleucodine is being investigated for its potential use in traditional medicine, leveraging its diverse bioactive properties for the treatment of various ailments.
Check Digit Verification of cas no
The CAS Registry Mumber 36150-07-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,6,1,5 and 0 respectively; the second part has 2 digits, 0 and 7 respectively.Calculate Digit Verification of CAS Registry Number 36150-07:
(7*3)+(6*6)+(5*1)+(4*5)+(3*0)+(2*0)+(1*7)=89
89 % 10 = 9
So 36150-07-9 is a valid CAS Registry Number.
InChI:InChI=1/C15H16O3/c1-7-4-5-10-9(3)15(17)18-14(10)13-8(2)6-11(16)12(7)13/h6,10,13-14H,3-5H2,1-2H3/t10-,13-,14-/m0/s1
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dehydroleucodine
