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PDDHV, or resiniferatoxin-type phorboid vanilloid, is a compound that selectively targets the cloned rat transient receptor potential cation channel subfamily V member 1 (TRPV1), also known as vanilloid receptor 1. It is similar to capsaicin and has the ability to induce Ca2+-uptake in rat dorsal root ganglion neurons with an EC50 value of 70 nM.

179469-40-0

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179469-40-0 Usage

Uses

Used in Pharmaceutical Industry:
PDDHV is used as a therapeutic agent for targeting the TRPV1 receptor, which is involved in various pain and inflammatory conditions. Its selective action on this receptor makes it a potential candidate for the development of novel pain relief medications and treatments for inflammatory disorders.
Used in Research Applications:
PDDHV is used as a research tool for studying the function and role of the TRPV1 receptor in cellular processes. Its ability to selectively target this receptor allows researchers to gain a better understanding of the underlying mechanisms involved in pain perception and other related conditions.
Used in Drug Delivery Systems:
Similar to gallotannin, PDDHV can also be incorporated into drug delivery systems to enhance its efficacy and bioavailability. By using carriers such as organic and metallic nanoparticles, the delivery, targeting, and therapeutic outcomes of PDDHV can be improved, making it a more effective treatment option for various conditions.

Check Digit Verification of cas no

The CAS Registry Mumber 179469-40-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,4,6 and 9 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 179469-40:
(8*1)+(7*7)+(6*9)+(5*4)+(4*6)+(3*9)+(2*4)+(1*0)=190
190 % 10 = 0
So 179469-40-0 is a valid CAS Registry Number.

179469-40-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 13, 2017

Revision Date: Aug 13, 2017

1.Identification

1.1 GHS Product identifier

Product name PDDHV

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:179469-40-0 SDS

179469-40-0Upstream product

179469-40-0Downstream Products

179469-40-0Relevant academic research and scientific papers

Similarities and differences in the structure-activity relationships of capsaicin and resiniferatoxin analogues

Walpole, Christopher S. J.,Bevan, Stuart,Bloomfield, Graham,Breckenridge, Robin,James, Iain F.,Ritchie, Timothy,Szallasi, Arpad,Winter, Janet,Wrigglesworth, Roger

, p. 2939 - 2952 (1996)

Structure-activity relationships in analogues of the irritant natural product capsaicin have previously been rationalized by subdivision of the molecule into three structural regions (A, B, and C). The hypothesis that resiniferatoxin (RTX), which is a hig

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