179469-40-0 Usage
Description
PDDHV is a resiniferatoxin-type phorboid vanilloid with capsaicin-like selectivity for the cloned rat transient receptor potential cation channel subfamily V member 1 (TRPV1), formerly known as vanilloid receptor 1. It induces Ca2+-uptake by rat dorsal root ganglion neurons with an EC50 value of 70 nM.
Check Digit Verification of cas no
The CAS Registry Mumber 179469-40-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,7,9,4,6 and 9 respectively; the second part has 2 digits, 4 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 179469-40:
(8*1)+(7*7)+(6*9)+(5*4)+(4*6)+(3*9)+(2*4)+(1*0)=190
190 % 10 = 0
So 179469-40-0 is a valid CAS Registry Number.
179469-40-0Relevant articles and documents
Similarities and differences in the structure-activity relationships of capsaicin and resiniferatoxin analogues
Walpole, Christopher S. J.,Bevan, Stuart,Bloomfield, Graham,Breckenridge, Robin,James, Iain F.,Ritchie, Timothy,Szallasi, Arpad,Winter, Janet,Wrigglesworth, Roger
, p. 2939 - 2952 (1996)
Structure-activity relationships in analogues of the irritant natural product capsaicin have previously been rationalized by subdivision of the molecule into three structural regions (A, B, and C). The hypothesis that resiniferatoxin (RTX), which is a hig
