179472-08-3

Upstream product

• 179472-07-2 Isobutyric acid (R)-3-benzyloxy-2-tert-butoxycarbonylamino-propyl ester 
• 79069-15-1 tert-butyl N-[(1S)-1-(benzyloxymethyl)-2-hydroxy-ethyl]carbamate 
• 47173-80-8 N-Boc-D-serine(Bzl)-OH 
• 10433-52-0 O-benzyl-D-serine 
• 20924-05-4 thymidyl acetic acid 

Downstream Products

• 179472-10-7 Isobutyric acid (R)-3-[bis-(4-methoxy-phenyl)-phenyl-methoxy]-2-[2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetylamino]-propyl ester 
• 179472-11-8 N-{(S)-2-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-1-hydroxymethyl-ethyl}-2-(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetamide 

Relevant academic research and scientific papers

Amino acid nucleic acids: Synthesis and hybridization properties of a novel class of antisense oligonucleotides

Oligonucleotides containing novel phoshoramidite 12 were synthesized and studied for their hybridization properties for the first time. Interestingly, these modified oligonucleotides showed a remarkable resistance to exonuclease.