17952-63-5

Basic information

• Product Name: 6-METHOXY-1 2 3 4-TETRAHYDRO-9H-PYRIDO-&
• Synonyms: 6-METHOXY-1 2 3 4-TETRAHYDRO-9H-PYRIDO-&;6-methoxy-1,2,3,4-tetrahydro-β-carboline-1-carboxylic acid;6-methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4b]indolecarboxyl;6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-1-carboxylic acid;6-methoxy-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-1-carboxylic acid
• CAS NO: 17952-63-5
• Molecular Formula: C₁₃H₁₄N₂O₃
• Molecular Weight: 246.265
• Mol File: 17952-63-5.mol
• Article Data: 4

Chemical Properties

• Melting Point: 217 °C (dec.)(lit.)
• Boiling Point: 524.8 °C at 760 mmHg
• Flash Point: 271.2 °C
• Appearance: /
• Density: 1.36 g/cm³
• Vapor Pressure: 7.7E-12mmHg at 25°C
• Refractive Index: 1.66
• CAS DataBase Reference: 6-METHOXY-1 2 3 4-TETRAHYDRO-9H-PYRIDO-&(CAS DataBase Reference)
• NIST Chemistry Reference: 6-METHOXY-1 2 3 4-TETRAHYDRO-9H-PYRIDO-&(17952-63-5)
• EPA Substance Registry System: 6-METHOXY-1 2 3 4-TETRAHYDRO-9H-PYRIDO-&(17952-63-5)

Safety Data

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39
• WGK Germany: 3
• Hazardous Substances Data: 17952-63-5(Hazardous Substances Data)

Usage

Uses

6-Methoxy-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole-1-carboxylic Acid is a stain/dye. Dyes and metabolites.

InChI:InChI=1/C13H14N2O3/c1-18-7-2-3-10-9(6-7)8-4-5-14-12(13(16)17)11(8)15-10/h2-3,6,12,14-15H,4-5H2,1H3,(H,16,17)

Upstream product

• 608-07-1 2-(5-methoxyindol-3-yl)ethylamine 
• 298-12-4 Glyoxilic acid 
• 66-83-1 5-methoxytryptamine hydrochloride 

Downstream Products

• 88704-49-8 eudistomin Q 
• 88704-39-6 eudistomin M 
• 58982-28-8 6-Hydroxy-beta-Carboline 
• 20315-68-8 pinoline 

Relevant articles and documents

Peganumine A alkaloid structure simplifier and application thereof

The invention discloses a Peganumine A alkaloid structure simplifier, a stereoisomer or a pharmaceutical salt thereof. The structure is shown in the following general formula: each substituent group is defined in the specification. The simplified structure of the Peganumine A alkaloid provided by the invention has a relatively obvious proliferation inhibition effect on liver cancer HepG2, lung cancer A549 and intestinal cancer HCT116, and the anti-tumor activity of part of compounds is higher than the anti-liver cancer HepG2 activity of Peganumine A reported in literatures.

6-Hydroxy- and 6-methoxy-β-carbolines as acetyl- and butyrylcholinesterase inhibitors

In the course of studies directed toward the discovery of novel acetyl- and butyrylcholinesterase (AChE and BChE) inhibitors for the treatment of Alzheimer's disease, we focused on β-carbolines (BCs). 6-Oxygenated β-carboline and β-carbolinium derivatives based on the serotonin template were synthesized and tested in vitro for their ability to inhibit AChE and BChE, respectively. Particularly the carbolinium salts, which can be formed by intracerebral methylation out of the tertiary-BC prodrugs, show inhibitory activity levels reaching those of galantamine, physostigmine, and rivastigmine.