226570-06-5

Basic information

• Product Name: (3-nitro-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester
• CAS NO: 226570-06-5
• Molecular Weight: 358.394
• Mol File: 226570-06-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (3-nitro-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (3-nitro-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester(226570-06-5)
• EPA Substance Registry System: (3-nitro-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester(226570-06-5)

Safety Data

• Hazardous Substances Data: 226570-06-5(Hazardous Substances Data)

Upstream product

• 171559-74-3 tert-butyl 2-(3-nitro-2-oxopyridin-1(2H)-yl)acetate 

Downstream Products

• 179526-01-3 [2-oxo-4-phenethyl-3-(trifluoro-ethanesulfonylamino)-2H-pyridin-1-yl]-acetic acid tert-butyl ester 
• 179526-06-8 [2-oxo-4-phenethyl-3-(trifluoro-ethanesulfonylamino)-2H-pyridin-1-yl]-acetic acid 
• 179526-02-4 (3-benzenesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester 
• 179526-07-9 (3-benzenesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid 
• 179526-03-5 C₂₀H₂₇N₃O₅S 
• 179526-00-2 (3-methanesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid tert-butyl ester 
• 179526-08-0 C₁₆H₁₉N₃O₅S 
• 179526-05-7 (3-methanesulfonylamino-2-oxo-4-phenethyl-2H-pyridin-1-yl)-acetic acid 
• 179524-59-5 t-butyl [3-amino-2-oxo-4-(2-phenylethyl)-1,2-dihydropyridyl]acetate 

Relevant articles and documents

Investigation of the S3 site of thrombin: Design, synthesis and biological activity of 4-substituted 3-amino-2-pyridones incorporating P1- argininals

A novel scaffold for P4-P2 dipeptide mimics containing a rigid pyridone spacer was designed based on a virtual library strategy. Several selected nonpeptidic 4-aralkyl or 4-alkylpyridones incorporating a P1- argininal sequence were prepared. The modeling studies, synthesis and biological activities of these unique pyridone derivatives are reported herein.