179533-91-6

Basic information

• Product Name: (S)-tert-butyl 3,3-dimethyl-1-oxo-1-(phenylamino)butan-2-ylcarbamate
• Synonyms: (S)-tert-butyl 3,3-dimethyl-1-oxo-1-(phenylamino)butan-2-ylcarbamate
• CAS NO: 179533-91-6
• Molecular Weight: 306.405
• Mol File: 179533-91-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-tert-butyl 3,3-dimethyl-1-oxo-1-(phenylamino)butan-2-ylcarbamate(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-tert-butyl 3,3-dimethyl-1-oxo-1-(phenylamino)butan-2-ylcarbamate(179533-91-6)
• EPA Substance Registry System: (S)-tert-butyl 3,3-dimethyl-1-oxo-1-(phenylamino)butan-2-ylcarbamate(179533-91-6)

Safety Data

• Hazardous Substances Data: 179533-91-6(Hazardous Substances Data)

Upstream product

• 62965-35-9 N-tert-butyloxycarbonyl-L-tert-leucine 
• 62-53-3 aniline 

Downstream Products

• 1430747-35-5 (S)-N²,3,3-trimethyl-N¹-phenylbutane-1,2-diamine 
• 1430747-39-9 (4S)-4-tert-butyl-2-chloro-3-methyl-1-phenyl-1,3,2-diazaphospholidine 
• 1430747-44-6 (4S)-4-tert-butyl-3-methyl-1-phenyl-2-(tricyclo[3.3.1.1.^3′,7′]dec-1′-yloxy)-1,3,2-diazaphospholidine 
• 171764-05-9 (S)-tert-butylglycine phenylamide 

Relevant articles and documents

Development of Plowast-monodentate diamidophosphites with a C1-symmetric 1,2-diamine backbone: The effects of substituents in the 1,3,2-diazaphospholidine cycle on Pd-catalyzed asymmetric allylations

We have designed and synthesized a small library of modular monodentate diamidophosphite ligands with stereogenic phosphorus atoms. The library was prepared efficiently from the commercially available and inexpensive (S)-N-Boc-amino acids. These novel ligands were screened in the Pd-catalyzed asymmetric allylations of (E)-1,3-diphenylallyl acetate with dimethyl malonate as the C-nucleophile with up to 93% ee being obtained. The results showed that the different substituents in the 1,3,2-diazaphospholidine cycle had remarkable effects on the enantioselectivity.