179534-94-2

Upstream product

• 76-83-5 trityl chloride 
• 17929-90-7 3-aminoazepan-2-one 
• 29426-64-0 (R)-α-amino-ε-caprolactam hydrochloride 
• 70-54-2 2,6-diaminocaproic acid 

Downstream Products

• 478828-64-7 1-benzyl-3-(tritylamino)-2-azepanone 
• 134907-68-9 1-benzyl-3-amino-hexahydroazepine 
• 478828-65-8 1-benzyl-N-trityl-3-azepanamine 
• 179535-36-5 1-ethyl-3-triphenylmethylamino-1H-hexahydroazepine 
• 188192-55-4 1-methylazepan-3-amine 
• 206434-38-0 1-methyl-3-(trityl-amino)-azepan-2-one 
• 206434-39-1 1-propyl-3-(trityl-amino)-azepan-2-one 
• 179535-35-4 1-ethyl-3-triphenylmethylamino-1H-hexahydroazepin-2-on 
• 206434-40-4 1-isopropyl-3-(trityl-amino)-azepan-2-one 

Relevant academic research and scientific papers

6-methoxy-1H-benzotriazole-5-carboxamide derivatives and pharmaceutical compositions containing them

6-Methoxy-1H-benzotriazole-5-carboxamide derivatives which are represented by the formula (I) below: STR1 ?in which R1 stands for ethyl or cyclopropylmethyl group, R2 stands for hydrogen atom, methyl or ethyl group, n is 1, 2 or 3, a

A novel series of N-(hexahydro-1,4-diazepin-6-yl) and N-(hexahydroazepin-3-yl)benzamides with high affinity for 5-HT3 and dopamine D2 receptors

A novel series of benzamides with a hexahydro-1,4-diazepine or hexahydroazepine ring in the amine moiety were prepared, and their binding affinities for 5-HT3 and dopamine 4 receptors were evaluated. The R isomer of the 1-ethyl-4-methylhexahydro-1,4-diazepinylbenzamide (R)-22 had potent affinity for both receptors. The R-enantiomer of the corresponding 1-ethylhexahydroazepinylbenzamide 28 showed potent affinity for dopamine D2 receptors with reduced affinity for 5-HT3 receptors, while the S isomer was found to be a potent and selective 5-HT3 receptor antagonist.