17954-08-4Relevant academic research and scientific papers
Synthesis of imidazol[1,5-a]indole-1,3-diones from imidazolidene-2,4-diones
Akeng'a,Read
, p. 11 - 16 (2008/09/16)
Copper and tributyltin hydride catalysed cyclization, through the N-aryl bond formation, of imidazolidine-2,4-diones (11-16,18) yielded imidazo[1,5-a]indole-1,3-diones (5-10) in high yields (72-100%). The ease of cyclization was found to be consistent with the normal halogen reactivity and the type of substituents. The highly substituted imidazole-2,4-dione 15 gave brominated 19 and tin incorporated heterocycles 20 when treated with copper bromide and tributyltin hydride, respectively.
Silver(I) ion-mediated desulfurization-cyclization of isothiocyanates with several hydroxy acids and N-substituted amino acids
Shibuya, Isao,Goto, Midori,Shimizu, Masao,Yanagisawa, Masaru,Gama, Yasuo
, p. 2667 - 2673 (2007/10/03)
The title reaction of 2-hydroxy-2-methylpropionic acid with phenyl isothiocyanate gave 5,5-dimethyl-3-phenyl-2,4-oxazolidinedione. The structure was determined by X-Ray crystal analysis, and the reaction pathway was estimated. The reactions of other 2-hyd
